Results 181 to 190 of about 11,135 (204)

Cell Removal: Efferocytosis

Annual Review of Cell and Developmental Biology, 2017
In metazoans, removal of cells in situ is involved in larval maturation, metamorphosis, and embryonic development. In adults, such cell removal plays a role in the homeostatic maintenance of cell numbers and tissue integrity as well as in the response to cell injury and damage.
openaire   +2 more sources

The Tim gene family in efferocytosis

Genes & Genomics, 2020
One of the key features of the plasma membrane is the asymmetrical distribution of phospholipids across it. Especially, phosphatidylserine (PS) exclusively locates on its inner leaflet. Thus, the exposure of PS on the surface of cells could function as a signal initiating various cellular processes such as phagocytosis of apoptotic cells called ...
Deokhwan Kim, Sang-Ah Lee, Hyunji Moon, Kwanhyeong Kim, Daeho Park   +4 more
openaire   +2 more sources

Efferocytosis in inflammatory bone disorders

Trends in Pharmacological Sciences
Efferocytosis, the clearance of apoptotic cells (ACs) by phagocytes, is crucial for bone homeostasis and immune balance. This tightly regulated process depends on molecular markers such as phosphatidylserine on ACs and MERTK on phagocytes. In the bone microenvironment, multiple cell types participate in efferocytosis, including osteal macrophages ...
Daowei Li
exaly   +3 more sources

The Role of Extracellular Vesicles in Efferocytosis

Mini-Reviews in Medicinal Chemistry
Abstract: Efferocytosis is the physiological process of phagocytic clearance of apoptotic cells by both professional phagocytic cells, such as macrophages, and non-professional phagocytic cells, such as epithelial cells. This process is crucial for maintaining tissue homeostasis in normal physiology.
Susan, Panahi, Zohreh, Yazdi, Mahboubeh, Sanchouli, Fatemehsadat, Sajadi, Fateme, Motavasselian, Hedyeh, Maghareh Abed, Zahra, Beygi, Seyed Mohammad, Gheibihayat   +7 more
openaire   +2 more sources

Macrophage cannibalism: efferocytosis in atherosclerosis

Current Opinion in Lipidology
Purpose of review This review explores the evolving understanding of efferocytosis – the clearance of dead or dying cells by phagocytes – in the context of atherosclerosis. It highlights recent discovers in cell death modalities, impaired clearance mechanisms and emerging therapeutic strategies aimed at ...
Amy A, Baxter, Ivan K H, Poon, Denuja, Karunakaran   +2 more
openaire   +2 more sources

Efferocytosis induces macrophage proliferation to help resolve tissue injury

Cell Metabolism, 2021
Xiaobo Wang, Wei Tao, Jinjun Shi
exaly  

Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

Immunity, 2023
Zhenyu Zhong, Qifeng He
exaly  

Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments

Cell Metabolism, 2023
Justin Perry, Waleska Saitz Rojas
exaly  

Efferocytosis

2015
Nikko Brix, Anna Tiefenthaller, Kirsten Lauber   +2 more
openaire   +1 more source

The ABCA1-efferocytosis axis: A new strategy to protect against atherosclerosis

Clinica Chimica Acta, 2021
Renshuai Zhang, Shuai Wang
exaly