Results 111 to 120 of about 8,614,944 (389)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Protective Effects of Nintedanib against Polyhexamethylene Guanidine Phosphate-Induced Lung Fibrosis in Mice

Molecules, 2018
Nintedanib (NDN), a tyrosine kinase inhibitor, has been shown to have anti-tumor, anti-inflammatory, and anti-fibrotic effects in several reports. We investigated the protective effects of NDN against polyhexamethylene guanidine phosphate (PHMG)-induced ...
Hyeon-Young Kim, Min-Seok Kim, Sung-Hwan Kim, Doin Joen, Kyuhong Lee   +4 more
doaj   +1 more source

The role of perceived self-efficacy in the development of musical ability: what can the study of successful musicians tell us about teaching music to able children?

, 2011
The role of perceived self-efficacy is important to human social development and to learning in general, but how it relates to music talent development is not well understood.
Areglado R.J., Bandura A., Creech A., Dweck C.S., Good C., Renzulli J.S., Sloboda J.A.   +6 more
core   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Control efficacy of complex networks [PDF]

, 2016
Acknowledgements W.-X.W. was supported by CNNSF under Grant No. 61573064, and No. 61074116 the Fundamental Research Funds for the Central Universities and Beijing Nova Programme, China. Y.-C.L.
Gao, Xin-Dong, Lai, Ying-Cheng, Wang, Wen-Xu   +2 more
core   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Research on the Mechanism and Material Basis of Corn (Zea mays L.) Waste Regulating Dyslipidemia

Pharmaceuticals
Corn (Zea mays L.) is an essential gramineous food crop. Traditionally, corn wastes have primarily been used in feed, harmless processing, and industrial applications. Except for corn silk, these wastes have had limited medicinal uses. However, in recent
Xiaodong Wang, Lewei Cao, Jiajun Tang, Jiagang Deng, Erwei Hao, Gang Bai, Pei Ling Tang, Jieyi Yang, Huaying Li, Lihao Yao, Cuiwei He, Xiaotao Hou   +11 more
doaj   +1 more source

The antioxidant activities of Korean Red Ginseng (Panax ginseng) and ginsenosides: A systemic review through in vivo and clinical trials

Journal of Ginseng Research, 2021
A wide range of studies have steadily pointed out the relation of oxidative stress to the primary and secondary causes of human disease and aging. As such, there have been multiple misconceptions about oxidative stress.
Soo Kyung Park, Sun Hee Hyun, Gyo In, Chae-Kyu Park, Yi-Seong Kwak, Young-Jin Jang, Bumseok Kim, Jong-Hoon Kim, Chang-Kyun Han   +8 more
doaj  

Mothers who are Refugees: An analysis of trauma, social support, and parenting efficacy. [PDF]

, 2017
The following exploratory correlational study examined the relationships among trauma severity, social support, and parenting self-efficacy in a sample of mothers who are refugees living in Vermont.
Papka, Sophia Valeria
core   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source