Results 31 to 40 of about 8,924,877 (409)

miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma

open access: yesFrontiers in Oncology, 2021
MicroRNAs are a group of endogenous small non-coding RNAs commonly dysregulated in tumorigenesis, including glioblastoma (GBM), the most malignant brain tumor with rapid proliferation, diffuse invasion, and therapeutic resistance.
Hongkun Qin   +8 more
doaj   +1 more source

Efficacy of Topiramate [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1998
ABSTRACT:In controlled clinical trials, topiramate (TopamaxR) has demonstrated efficacy in refractory patients with complex partial seizures and secondarily generalized tonic-clonic seizures. Approximately 45 percent of 534 patients had a ≥ 50 percent reduction in seizure frequency.
openaire   +3 more sources

Coaching efficacy and coaching effectiveness: examining their predictors and comparing coaches' and athletes' reports [PDF]

open access: yes, 2008
Research on the conceptual model of coaching efficacy (Feltz, Chase, Moritz, & Sullivan, 1999) has increased dramatically over the past few years. Utilizing this model as the guiding framework, the current study examined: (a) coaching experience and sex ...
Boardley, Ian David   +4 more
core   +1 more source

Immuno-enhancement effects of Korean Red Ginseng in healthy adults: a randomized, double-blind, placebo-controlled trial

open access: yesJournal of Ginseng Research, 2021
Background: Most clinical studies of immune responses activated by Korean Red Ginseng (KRG) have been conducted exclusively in patients. However, there is still a lack of clinical research on immune-boosting benefits of KRG for healthy persons.
Sun Hee Hyun   +7 more
doaj   +1 more source

Self-efficacy, religiosity, and crime: profiles of African American youth in urban housing communities [PDF]

open access: yes, 2017
Youth reporting independently elevated levels of religiosity and self-efficacy tend to abstain from externalizing behavior. However, little is known about the ways in which religiosity and self-efficacy interrelate to impact youth externalizing.
Lombe, Margaret   +4 more
core   +1 more source

Political Efficacy

open access: yes, 2023
A fundamental question asked in early survey-based political communication research is whether people feel that their political actions can affect political processes. Research has consistently shown the centrality of this political attitude, known as “political efficacy,” for democratic functioning. In recent research, political communication scholars
openaire   +1 more source

Identification and Analysis of Components in Yizhi Granule and Cynomolgus Monkey Plasma after Oral Administration by UPLC/ESI-Q-TOF MS and Their Protective Effects on PC12 Cells

open access: yesJournal of Analytical Methods in Chemistry, 2020
Yizhi Granule (YZG) is a health food containing six traditional Chinese medicines (TCMs). It improves memory barriers in rat experiments. Here, we describe the first fast and sensitive ultraperformance liquid chromatography/electrospray ionization ...
Erwei Hao   +11 more
doaj   +1 more source

Anti-Osteoporotic Effect of Viscozyme-Assisted Polysaccharide Extracts from Portulaca oleracea L. on H2O2-Treated MC3T3-E1 Cells and Zebrafish

open access: yesSeparations, 2022
This study aims to screen and characterize the protective effect of polysaccharides from Portulaca oleracea L. (POP) against H2O2-stimulated osteoblast apoptosis in vivo and in vitro.
Yunhua Fu   +8 more
doaj   +1 more source

Bone marrow mesenchymal stem cell-derived exosomal microRNA regulates microglial polarization [PDF]

open access: yesPeerJ, 2023
Objective This study aimed to explore the effects of bone marrow mesenchymal stem cell (BMSC)-derived exosomal miR-146a-5p on microglial polarization and the potential underlying mechanisms in oxygen-glucose deprivation (OGD)-exposed microglial cells ...
Xianwei Huang   +5 more
doaj   +2 more sources

Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line antimalarials in Nigeria

open access: yesInfectious Diseases of Poverty, 2019
Background The development and spread of artemisinin-resistant Plasmodium falciparum malaria in Greater Mekong Subregion has created impetus for continuing global monitoring of efficacy of artemisinin-based combination therapies (ACTs).
Akintunde Sowunmi   +35 more
doaj   +1 more source

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