Results 71 to 80 of about 8,363,616 (384)

Physiological and pharmacological features of the non-saponin components in Korean Red Ginseng

Journal of Ginseng Research, 2020
Panax ginseng, a medicinal plant, has been used as a blood-nourishing tonic for thousands of years in Asia, including Korea and China. P. ginseng exhibits adaptogen activity that maintains homeostasis by restoring general biological functions and non ...
Sun Hee Hyun, Sung Won Kim, Hwi Won Seo, Soo Hyun Youn, Jong Soo Kyung, Yong Yook Lee, Gyo In, Chae-Kyu Park, Chang-Kyun Han   +8 more
doaj  

Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine

New England Journal of Medicine, 2021
Background The safety and efficacy of the AZD1222 (ChAdOx1 nCoV-19) vaccine in a large, diverse population at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United States, Chile, and Peru has not been ...
A. Falsey, M. Sobieszczyk, I. Hirsch, Stephanie Sproule, M. Robb, L. Corey, K. Neuzil, William W Hahn, Julie Hunt, M. Mulligan, C. Mcevoy, E. Dejesus, Michael Hassman, S. Little, B. Pahud, A. Durbin, P. Pickrell, E. Daar, L. Bush, Joel Solis, Quito Osuna Carr, Temitope Oyedele, S. Buchbinder, J. Cowden, Sergio L Vargas, Alfredo Guerreros Benavides, R. Call, M. Keefer, B. Kirkpatrick, J. Pullman, T. Tong, Margaret Brewinski Isaacs, David C. Benkeser, H. Janes, M. Nason, Justin A. Green, E. Kelly, Jill Maaske, N. Mueller, Kathryn Shoemaker, Therese Takas, Richard P. Marshall, M. Pangalos, T. Villafana, Antonio Gonzalez-Lopez   +44 more
semanticscholar   +1 more source

Moments of clarity : a study of higher education teachers' professional learning experiences and the transformational process of change in self-efficacy development : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Education at Massey University, Manawatū, New Zealand [PDF]

, 2017
This qualitative longitudinal study sought to understand ‘aha’ moments experienced by a group of early career higher education teachers in Aotearoa New Zealand and the role those moments played in the transformational process of change in teacher self ...
Percy, Bridget Marie
core  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Field efficacy of new compounds to replace copper for scab control in organic apple production [PDF]

, 2007
Efficacy of compounds was investigated in field experiments in Denmark and the Netherlands according to EPPO guidelines. Some Yucca extracts and potassium bicarbonate had an efficacy similar to sulphur on leaves.
Bengtsson, M., de Jong, P.F., Heijne, B., Hockenhull, J., Lindhard Pedersen, H., Paaske, K.   +5 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Immuno-enhancement effects of Korean Red Ginseng in healthy adults: a randomized, double-blind, placebo-controlled trial

Journal of Ginseng Research, 2021
Background: Most clinical studies of immune responses activated by Korean Red Ginseng (KRG) have been conducted exclusively in patients. However, there is still a lack of clinical research on immune-boosting benefits of KRG for healthy persons.
Sun Hee Hyun, Ha-Young Ahn, Hyeong-Jun Kim, Sung Won Kim, Seung-Ho So, Gyo In, Chae-Kyu Park, Chang-Kyun Han   +7 more
doaj  

Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone. [PDF]

, 2006
OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment. We evaluated the efficacy of this combination in Kailahun, where a previous study had shown 70.2% efficacy of amodiaquine in monotherapy.
Balkan, S, Checchi, F, Durand, R, Grandesso, F, Guthmann, J P, Hagerman, A, Kamara, S, Lam, E, Scollo, G   +8 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source