Results 101 to 110 of about 2,589,705 (354)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

ENERGY EFFICIENCY IN THE FOOD RETAIL [PDF]

Business Excellence and Management, 2016
In this paper the emphasis is put on the specifics of energy efficiency impact on the profitability of the service sector, with special insight into food retail. The theoretical and methodological presentations are illustrated by applying the comparative
Radojko LUKIC
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

LEESOLA: A Locally Made Energy Efficient Solar Tracking System for Home Use

Techne
A solar tracking system is used to orient solar reflectors, photovoltaic panels, and other solar energy harvesting equipment toward the sun mainly to maximize energy output.
Benjamin Kommey, Elvis Tamakloe, Agbesi Jerry, Darkwa Wassem, Normenyo Gershon Elikem   +4 more
doaj   +1 more source

Keynote address: efficient use of energy [PDF]

WIT Transactions on Engineering Sciences, 2012
All primary energy sources, such as oil, gas, coal, nuclear and hydro need to be converted into end-user energy services known as mechanical work, electricity, heating and cooling. In the process of conversion, only a portion of the primary energy is transformed into the new form, while the rest remains unaltered and is lost.
openaire   +2 more sources

Scenarios of energy efficiency and CO2 emissions reduction potential in the buildings sector in China to year 2050 [PDF]

, 2018
As China’s rapid urbanization continues and urban dwellers become more affluent, energy use in buildings is expected to grow. To understand how this growth can be slowed, we explore four scenarios for Chinese buildings, ranging from a high-energy-demand ...
Feng, W, Ke, J, Khanna, N, Levine, M, Zhou, N   +4 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

The European Union and the Alternative Sources of Energy [PDF]

The paper presents a detailed analysis of the alternative sources of energy and aspects related to the efficient use of these sources.Energy; Alternative sources of energy; Renewable energy.
Camelia Georgeta CALIN, Claudia SIMA
core  

Efficient energy use and renewable sources of energy in Slovenia [PDF]

, 2013
This paper presents unique survey results with opinions on the competitive supply and efficient energy use, sources of energy and renewable sources of energy.
Bojnec, Štefan, Papler, Drago
core   +1 more source