Noncatalytic Functions Are Required for MPO and PON1 in Modulating the Involvement of Monocytes and Endothelial Cells in Atherosclerosis. [PDF]
Biochem Res IntLi Y, Liu Y, Cheng Y.
europepmc +1 more source
Advanced Science, EarlyView.Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
<i>In Vitro</i> BBB triculture assay and preliminary computational model development to predict brain exposure. [PDF]
Front ToxicolXu ZM, Sluka JP, Zhang CC, Knipp G.
europepmc +1 more source
3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction
Advanced Science, EarlyView.A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley +1 more source
MEMBRANE INTEGRITY IN LEAVES OF BARLEY INFECTED BY BROWN RUST: AN EXAMINATION USING TRACER EFFLUX AND IN VIVO CHLOROPHYLL FLUORESCENCE [PDF]
, 1985 Iftikhar Ahmad +2 more
openalex +1 more source
Molecular insights into efflux pump genes in ciprofloxacin- and methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis clinical isolates from Iraq. [PDF]
Sci RepJameel TY, Idris AB, Salman MA, Ayvaz A.
europepmc +1 more source
Advanced Science, EarlyView.SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
Mechanistic Studies of ArsA ATPase and ArsB Transporter of the Bacterial Arsenite Efflux System
Mahajan, Shivansh
openalex +1 more source
Downregulation of Expression of Xenobiotic Efflux Genes is Associated with Pelvic Pouch Inflammation in Ulcerative Colitis [PDF]
, 2014 Boyko Kabakchiev +4 more
openalex +1 more source