Results 41 to 50 of about 427,575 (339)
Minocycline Susceptibility and tetB Gene in Carbapenem-Resistant Acinetobacter baumannii in Taiwan
Infection and Drug Resistance, 2022 Jia-Ling Yang,1 Chia-Jui Yang,2,3 Yu-Chung Chuang,1 Wang-Huei Sheng,1 Yee-Chun Chen,1 Shan-Chwen Chang1 1Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; 2Department of Internal Medicine, Far ...
Yang JL +5 more
doaj
Importance of macrophage cholesterol content on the flux of cholesterol mass
Journal of Lipid Research, 2010 Net flux of cholesterol represents the difference between efflux and influx and can result in net cell-cholesterol accumulation, net cell-cholesterol depletion, or no change in cellular cholesterol content.
Sandhya Sankaranarayanan +5 more
doaj +1 more source
Using cellular fitness to map the structure and function of a major facilitator superfamily effluxer. [PDF]
, 2017 The major facilitator superfamily (MFS) effluxers are prominent mediators of antimicrobial resistance. The biochemical characterization of MFS proteins is hindered by their complex membrane environment that makes in vitro biochemical analysis challenging.
Bennett, Matthew R +5 more
core +2 more sources
Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]
, 2017 Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio +8 more
core +2 more sources
Bacterial Multidrug Efflux Transporters [PDF]
Annual Review of Biophysics, 2014 Infections caused by bacteria are a leading cause of death worldwide. Although antibiotics remain a key clinical therapy, their effectiveness has been severely compromised by the development of drug resistance in bacterial pathogens. Multidrug efflux transporters—a common and powerful resistance mechanism—are capable of extruding a number of ...
Jared A, Delmar +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Journal of Integrative Agriculture, 2016 The objective of this study was to verify the supposition that efflux might be involved in the drug resistance of Riemerella anatipestifer isolates. Two broad-spectrum efflux pump inhibitors, carbonyl cyanide 3-chlorophenylhydrazone (CCCP) and Phe-Arg-β ...
Ya-fei LI +8 more
doaj +1 more source
D-mannose transport and metabolism in isolated enterocytes [PDF]
, 2004 D-mannose transport and metabolism has been studied in enterocytes isolated from chicken small intestine. In the presence of Na+, the mannose taken up by the cells either remains free, is phosphorylated, is catabolized to H2O, or becomes part of membrane
Cano Rodríguez, María Mercedes +3 more
core +1 more source
Multidrug Efflux Pumps in Bacteria and Efflux Pump Inhibitors
Postępy Mikrobiologii - Advancements of Microbiology, 2022 Abstract Antimicrobial resistance is becoming a paramount health concern nowadays. The increasing drug resistance in microbes is due to improper medications or over usage of drugs. Bacteria develop many mechanisms to extrude the antibiotics entering the cell. The most prominent are the efflux pumps (EPs).
Sreekantan Abhirami P. +3 more
openaire +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source