Results 61 to 70 of about 426,896 (336)

Efflux-mediated fluoroquinolone resistance in the multidrug-resistant Pseudomonas aeruginosa clinical isolate PA7: identification of a novel MexS variant involved in upregulation of the mexEF-oprN multidrug efflux operon

Frontiers in Microbiology, 2015
The emergence of multidrug-resistant Pseudomonas aeruginosa has become a serious problem in medical settings. P. aeruginosa clinical isolate PA7 is resistant to fluoroquinolones, aminoglycosides, and most -lactams but not imipenem.
Yuji eMorita, Junko eTomida, Yoshiaki eKawamura   +2 more
doaj   +1 more source

MmpS5-MmpL5 Transporters Provide Mycobacterium smegmatis Resistance to imidazo[1,2-b][1,2,4,5]tetrazines

Pathogens, 2020
The emergence and spread of drug-resistant Mycobacterium tuberculosis strains (including MDR, XDR, and TDR) force scientists worldwide to search for new anti-tuberculosis drugs.
Dmitry A. Maslov, Kirill V. Shur, Aleksey A. Vatlin, Valery N. Danilenko   +3 more
doaj   +1 more source

Study of the efflux velocity induced by two propellers [PDF]

, 2015
Present analysis is related with seabed erosion caused during docking and undocking maneuvering. Twin propellers without rudder were studied using a physical model with a fixed clearance distance and three different rotating velocities.
Gironella Cobos, Xavier, Gómez Gesteira, Moncho, Jaquet, A., Mujal Colilles, Anna, Sánchez-Arcilla Conejo, Agustín   +4 more
core  

The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY. [PDF]

, 2020
LacY catalyzes accumulation of galactosides against a concentration gradient by coupling galactoside and H+ transport (i.e., symport). While alternating access of sugar- and H+-binding sites to either side of the membrane is driven by binding and ...
Choi, Seo Woo, Ermolova, Natalia, Jiang, Xiaoxu, Kaback, H Ronald, Lim, John   +4 more
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Microbial Communities of the Providence River [PDF]

, 2015
The Providence River has been industrialized for over one-hundred years. Industries such as oil storage and metal recycling facilities have left high levels of pollutant metals, including lead (Pb), in the soil and water.
Kratch, Jacqueline
core   +1 more source

The significance of organic carbon and nutrient export from peatland-dominated landscapes subject to disturbance, a stoichiometric perspective [PDF]

, 2009
The terrestrial-aquatic interface is a crucial environment in which to consider the fate of exported terrestrial carbon in the aquatic system. Here the fate of dissolved organic carbon (DOC) may be controlled by nutrient availability.
Arlaud, C., Bryant, C., Flowers, H., McFarlane, S., Waldron, S.   +4 more
core   +2 more sources

Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy [PDF]

Journal of Antimicrobial Chemotherapy, 2015
The emergence of drug resistance continues to plague TB control, with a global increase in the prevalence of MDR-TB. This acts as a gateway to XDR-TB and thus emphasizes the urgency for drug development and optimal treatment options. Bedaquiline is the first new anti-TB drug approved by the FDA in 40 years and has been shown to be an effective ...
Caroline M, Pule, Samantha L, Sampson, Robin M, Warren, Philippa A, Black, Paul D, van Helden, Tommie C, Victor, Gail E, Louw   +6 more
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Negative Impact of Citral on Susceptibility of Pseudomonas aeruginosa to Antibiotics

Frontiers in Microbiology, 2021
Essential oils (EOs) or their components are widely used by inhalation or nebulization to fight mild respiratory bacterial infections. However, their interaction with antibiotics is poorly known. In this study we evaluated the effects of citral, the main
Alexandre Tetard, Sarah Foley, Gaëtan L. A. Mislin, Jean-Michel Brunel, Estefania Oliva, Freddy Torrealba Anzola, Andy Zedet, Bruno Cardey, Yann Pellequer, Christophe Ramseyer, Patrick Plésiat, Patrick Plésiat, Catherine Llanes   +12 more
doaj   +1 more source