Results 81 to 90 of about 427,575 (339)

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Understanding adaptation to fluconazole: comparative insights into tolerance and resistance in Saccharomyces cerevisiae and Candida albicans

Frontiers in Cellular and Infection Microbiology
IntroductionAntifungal resistance and tolerance are distinct responses exhibited by fungi when exposed to drugs. While considerable research has focused on azole tolerance in the human pathogen Candida albicans, studies in other fungal species remain ...
Lijun Zheng, Yubo Dong, Jing Wang, Yonghui Jia, Weifang Wang, Yi Xu, Yi Xu, Liangsheng Guo   +7 more
doaj   +1 more source

The Role of Transport Mechanisms in Mycobacterium Tuberculosis Drug Resistance and Tolerance

Pharmaceuticals, 2012
In the fight against tuberculosis, cell wall permeation of chemotherapeutic agents remains a critical but largely unsolved question. Here we review the major mechanisms of small molecule penetration into and efflux from Mycobacterium tuberculosis and ...
Jansy Passiflora Sarathy, Véronique Dartois, Edmund Jon Deoon Lee   +2 more
doaj   +1 more source

Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior [PDF]

, 2003
Prenatal nicotine exposure has been linked to attention deficit hyperactivity disorder and cognitive impairment, but the sites of action for these effects of nicotine are still under investigation. High-affinity nicotinic acetylcholine receptors (nAChRs)
Caldarone, Barbara J, Collins, Allan C, Grady, Sharon R, King, Sarah L, Koren, Andrei O, Marks, Michael J, Mukhin, Alexey G, Picciotto, Marina R   +7 more
core   +2 more sources

Unassisted Photoelectrochemical Hydrogen Production Coupled with Selective Glucose Oxidation Using Metal Halide Perovskite Photoanodes

Advanced Functional Materials, EarlyView.
A metal halide perovskite‐based photoanode integrated with a CoNiFe layered double hydroxide (LDH) cocatalyst is reported for selective glucose oxidation reaction (GOR), achieving simultaneous and unassisted photoelectrochemical hydrogen production. This system delivers high photocurrent density, excellent Faradaic efficiency of GOR, and strong techno ...
Shujie Zhou, Xu Liu, Michael Gunawan, Yihao Shan, Ming Zhang, Shaine Lucas, Adhi Satriyatama, Denny Gunawan, Ao Wang, Xiaojie Yuan, Kaiwen Sun, Rose Amal, Xiaojing Hao   +12 more
wiley   +1 more source

Old carbon contributes to aquatic emissions of carbon dioxide in the Amazon [PDF]

, 2014
Knowing the rate at which carbon is cycled is crucial to understanding the dynamics of carbon transfer pathways. Recent technical developments now support measurement of the ¹⁴C age of evaded CO₂ from fluvial
Garnett, M.H., Newton, J., Vihermaa, L.E., Waldron, S.   +3 more
core   +2 more sources

Highly Sensitive Electrochemical Biosensor Based on Hairy Particles with Controllable High Enzyme Loading and Activity

Advanced Functional Materials, EarlyView.
For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin, Anila Antony, Hongtao Cai, Antonia Debevc, Ceyda Topal, Anne Linhardt, Alla Synytska, Leonid Ionov   +7 more
wiley   +1 more source

Induction of pan-azole resistance in Cryptococcus neoformans by agrochemical azole uniconazole through upregulation of efflux and chromosomal disomies

Frontiers in Cellular and Infection Microbiology
Cryptococcus neoformans is a fungus naturally found in the environment, particularly in soil, bird droppings, and trees. Cryptococcosis, caused by Cryptococcus spp., primarily C. neoformans and C.
Maoji Zhang, Maoji Zhang, Weihua Ma, Jing Wang, Jing Wang, Feng Yang, Jingjing Zhong, Yi Xu, Yi Xu   +8 more
doaj   +1 more source

Comparative effects of auxin and abscisic acid on growth, hydrogen ion efflux and gravitropism in primary roots of maize [PDF]

In order to test the idea that auxin action on root growth may be mediated by H(+) movement, the correlation of auxin action on growth and H(+) movement in roots was examined along with changes in H(+) efflux patterns associated with the asymmetric ...
Evans, M. L., Mulkey, T. J.
core   +1 more source

Root uptake of lipophilic zinc-rhamnolipid complexes [PDF]

, 2008
This study investigated the formation and plant uptake of lipophilic metal-rhamnolipid complexes. Monorhamnosyl and dirhamnosyl rhamnolipids formed lipophilic complexes with copper (Cu), manganese (Mn), and zinc (Zn). Rhamnolipids significantly increased
Hettiarachchi, Ganga M., Karkkainen, Michael, McLaughlin, Michael J., Scheckel, Kirk G., Stacey, Samuel P., Çakmak, İsmail   +5 more
core   +1 more source