Results 191 to 200 of about 63,241 (259)

Strain-dependent contribution of the AcrAB-TolC efflux pump to Klebsiella pneumoniae physiology

Bhogal K, Clough B, Emmerson C, Organ A, Chen Y, Buckner MM, Alav I.   +6 more
europepmc   +1 more source

The Resistance-Nodulation-Division efflux pump EefABC is highly conserved within lineages of <i>E. coli</i> commonly associated with infection. [PDF]

Microb Genom
Pugh HL, Darby EM, Burgess L, Colclough AL, John AM, Dunn S, Connor C, Perry EA, McNally A, Bavro VN, Blair JMA.   +10 more
europepmc   +1 more source

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Clinical <i>Klebsiella pneumoniae</i> isolates and their efflux pump mechanism for antibiotic resistance challenge. [PDF]

Open Vet J
Kadhum AA, Khudor MH, Ibraheim HK.
europepmc   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides. [PDF]

Elife
Lee KK, Łapińska U, Tolle G, Micaletto M, Zhang B, Phetsang W, Verderosa AD, Invergo BM, Westley J, Bebes A, Yuecel R, O'Neill PA, Farbos A, Jeffries AR, van Houte S, Caboni P, Blaskovich MAT, Housden BE, Tsaneva-Atanasova K, Pagliara S.   +19 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

<i>Mycobacterium tuberculosis</i> genomic surveillance in Mexico. Characterization of variants in drug resistance and efflux pump genes. [PDF]

Front Microbiol
Alvarado-Peña N, Muñoz Torrico M, Narváez-Díaz L, Mejía-Ponce PM, Becerril Vargas E, Zúñiga J, Muñiz-Salazar R, Laniado-Laborín R, Licona-Cassani C, Soberón X, Silva-Herzog E.   +10 more
europepmc   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Correction to 'MexR and NalD are pyocyanin-responsive transcriptional repressors of the efflux pump MexAB-OprM in Pseudomonas aeruginosa'. [PDF]

Nucleic Acids Res
europepmc   +1 more source