Results 221 to 230 of about 59,758 (308)

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Achieving superior therapeutic effects on methicillin‐resistant Staphylococcus aureus infection via simple sulfonation process for preparing zwitterionic photosensitizer

Interdisciplinary Medicine, EarlyView.
The sulfonated zwitterionic photosensitizer (PYSO3) is synthesized by reacting maleic anhydride derivatives with 4‐aminopyridine to form PY, followed by sulfonation with 1,4‐butane sultone. It exhibits both photothermal and photodynamic properties, enabling effective eradication of MRSA and biofilms, as well as promoting wound healing in mice ...
Changxu Zhu, Yin Li, Qiyun Deng, Ruixin Guo, Yu Huang, Wenyan Guo, Xi Chen, Ben Zhong Tang, Zhiming Wang, Lidan Chen, Zhaohui Sun   +10 more
wiley   +1 more source

Evaluation of the Activity of Amino Chalcone Against <i>Staphylococcus</i> Strains Harboring Efflux Pumps. [PDF]

Pharmaceuticals (Basel)
Donato IA, Barbosa CRDS, Bezerra AH, Bezerra SR, Almeida RS, Oliveira-Tintino CDM, Araújo IM, Rodrigues EYS, Oliveira MYC, Cajazeiras FF, Dias JML, Guedes JM, Cristino JHS, Marinho ES, Marinho MM, Santos HSD, Coutinho HDM, Tintino SR, de Menezes IRA, da Cunha FAB.   +19 more
europepmc   +1 more source

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin, Heloisa Amancio, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Tugstênio Lima de Souza, José Eduardo Vargas, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +7 more
wiley   +1 more source

Verapamil Suppresses the Development of Resistance Against Anti-Tuberculosis Drugs in Mycobacteria. [PDF]

Int J Mol Sci
Liu K, Buitenhek E, Kuijl CP, Mulla Y, Luirink J, Bald D.   +5 more
europepmc   +1 more source

Validation of Hexaplex Recombinase Polymerase Amplification Assay for the Detection of Carbapenemase Genes in Klebsiella pneumoniae Isolates From Pediatric Inpatients

Journal of Clinical Laboratory Analysis, EarlyView.
A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Suthawan Mutitanon, Nuntaree Chaichanawongsaroj   +1 more
wiley   +1 more source

Assembly and inhibition of transferable TMexCD1-TOprJ1 efflux pump. [PDF]

Nat Commun
Shi Y, Li M, Cui T, Gan J, Huang H, Su Z, Yang R, Zhang X, Zhang H, Feng Y, Feng Y.   +10 more
europepmc   +1 more source

Attaching the NorA Efflux Pump Inhibitor INF55 to Methylene Blue Enhances Antimicrobial Photodynamic Inactivation of Methicillin-Resistant Staphylococcus aureus in Vitro and in Vivo. [PDF]

ACS Infect Dis, 2017
Rineh A, Dolla NK, Ball AR, Magana M, Bremner JB, Hamblin MR, Tegos GP, Kelso MJ.   +7 more
europepmc   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Efflux systems driving resistance and virulence across biological domains. [PDF]

PeerJ
Almeida da Silva PE, Von Groll A, Ramis I, Reis AJ, Ramos D, Viveiros M.   +5 more
europepmc   +1 more source