Results 241 to 250 of about 59,758 (308)

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed   +7 more
wiley   +1 more source

Exogenous indole promotes florfenicol tolerance in <i>Edwardsiella tarda</i>. [PDF]

open access: yesVirulence
Zheng Y   +8 more
europepmc   +1 more source

CRISPR‐based genome editing reveals the roles of efflux pumps in Mycobacterium abscessus

open access: yesmLife, EarlyView.
Abstract Mycobacterium abscessus, one of the most antimicrobial‐resistant bacteria, is increasingly recognized as the cause of infections that are difficult to treat. Novel genetic manipulation tools are required to elucidate the biology, pathogenesis, and antibiotic resistance mechanisms of M. abscessus.
Sishang Li   +7 more
wiley   +1 more source

Efflux pumps in Mycobacterium tuberculosis : what is their role in multi-drug resistance? [PDF]

open access: yes, 2014
Roca Pascual, Núria   +1 more
core  

Resistance evolution under potentiated sulphonamide pressure in <i>Escherichia coli</i>. [PDF]

open access: yesFront Vet Sci
Kerek Á   +8 more
europepmc   +1 more source

Dynamic Contrast Enhanced—Magnetic Resonance Fingerprinting (DCE‐MRF) Improves Detection of Induced Vascular Perfusion Reduction in a Mouse Breast Cancer Model

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Dynamic contrast‐enhanced MRI (DCE‐MRI) can assess tumor perfusion using pharmacokinetic models. However, poor DCE‐MRI reproducibility from reliance on conventional T1‐weighted MRI has limited clinical translation. We evaluated whether Dynamic Contrast Enhanced‐Magnetic Resonance Fingerprinting (DCE‐MRF), which directly generates ...
Christina J. MacAskill   +15 more
wiley   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

open access: yesNano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri   +2 more
wiley   +1 more source

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