Results 261 to 270 of about 59,328 (312)

Synergistic activity of mupirocin in combination with protocatechuic acid ethyl ester against mupirocin-resistant MRSA. [PDF]

Front Cell Infect Microbiol
Shen L, Yang J, Chen Z, Fu J, Zhao H, Lv J, Huang Y, Yuan X, Gao H, Yu F, Lin C, Yu J.   +11 more
europepmc   +1 more source

Genetic variation and mutational determinants of azole resistance in Candida albicans strains of oropharyngeal colonization in HIV patients and bloodstream infections. [PDF]

J Biomed Sci
Tsai MH, Hsieh CH, Tsai IA, Chang CM, Chen TW, Hsu JF, Chu SM, Huang HR, Wang SH, Lu JJ.   +9 more
europepmc   +1 more source

Verapamil Suppresses the Development of Resistance Against Anti-Tuberculosis Drugs in Mycobacteria. [PDF]

Int J Mol Sci
Liu K, Buitenhek E, Kuijl CP, Mulla Y, Luirink J, Bald D.   +5 more
europepmc   +1 more source

Assembly and inhibition of transferable TMexCD1-TOprJ1 efflux pump. [PDF]

Nat Commun
Shi Y, Li M, Cui T, Gan J, Huang H, Su Z, Yang R, Zhang X, Zhang H, Feng Y, Feng Y.   +10 more
europepmc   +1 more source

Efflux systems driving resistance and virulence across biological domains. [PDF]

PeerJ
Almeida da Silva PE, Von Groll A, Ramis I, Reis AJ, Ramos D, Viveiros M.   +5 more
europepmc   +1 more source

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Efflux pump inhibitors: new updates

Pharmacological Reports, 2020
The discovery of antibiotics ought to have ended the issue of bacterial infections, but this was not the case as it has led to the evolution of various mechanisms of bacterial resistance against various antibiotics. The efflux pump remains one of the mechanisms through which organisms develop resistance against antibiotics; this is because organisms ...
Manaf AlMatar, Osman Albarri, Essam A. Makky, Fatih Köksal   +3 more
openaire   +2 more sources

New-generation efflux pump inhibitors

Expert Review of Clinical Pharmacology, 2008
The development of novel efflux pump inhibitors is an emerging and challenging research field. Besides the use of such excipients in cancer therapy, efflux pump inhibitors are gaining increasing interest with regards to drug delivery. In particular, inhibition of efflux pumps located in the intestine and the blood-brain barrier offers promising ...
Martin, Werle, Hirofumi, Takeuchi, Andreas, Bernkop-Schnürch   +2 more
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Efflux pump inhibitors in bacteria

Expert Opinion on Therapeutic Patents, 2007
The efficacy of antibiotherapy of infectious diseases is strongly compromised by the advent and spread of antibiotic resistance. Active efflux of cytotoxic drugs mediated by multi-drug transporters is the basis of multi-drug resistance in prokaryotic cells.
Sandrine Alibert, Jean-Marie Pagès
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Computational modelling of efflux pumps and their inhibitors [PDF]

Essays in Biochemistry, 2017
Antimicrobial resistance is based on the multifarious strategies that bacteria adopt to face antibiotic therapies, making it a key public health concern of our era. Among these strategies, efflux pumps (EPs) contribute significantly to increase the levels and profiles of resistance by expelling a broad range of unrelated compounds – buying time for the
RAMASWAMY, VENKATA KRISHNAN, CACCIOTTO, PIERPAOLO, MALLOCI, GIULIANO, VARGIU, ATTILIO VITTORIO, RUGGERONE, PAOLO   +4 more
openaire   +2 more sources