Results 191 to 200 of about 90,161 (342)

Methylation‐Induced Permanent Charge Polarization in Covalent Organic Frameworks for Visible Light‐Driven Water Decontamination and Disinfection

Advanced Science, EarlyView.
A targeted in situ methylation strategy is developed to engineer cationic centers in a quinoline‐linked COF (NQ‐COFS1‐Me), creating a strong built‐in electric field, which effectively suppresses excitonic effects and promotes charge separation. The optimized material demonstrates powerful photocatalytic ROS generation for rapid bacterial inactivation ...
Xuewen Peng, Huaji Pang, Niu Feng, Dekang Huang, Chunpeng Jiao, Jingbin Zeng, Yonggang Xiang, Yiping Chen   +7 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Structure and mechanism of a mycobacterial isoniazid efflux pump MsRv1273c/72c with a degenerate nucleotide-binding site [PDF]

Jing Yu, Y.‐X Lan, Chen Zhu, Zhendong Chen, Ji‐An Pan, Yanfeng Shi, Lan Yang, Tianyu Hu, Yan Gao, Yao Zhao, Xiaobo Chen, Xiuna Yang, Shuihua Lu, Luke W. Guddat, Haitao Yang, Zihe Rao, Jun Li   +16 more
openalex   +1 more source

Complete sequencing of an IncHI1 plasmid encoding the carbapenemase NDM-1, the ArmA 16S RNA methylase and a resistance-nodulation-cell division/multidrug efflux pump [PDF]

, 2012
Monika Dolejská, Laura Villa, Laurent Poirel, Patrice Nordmann, Alessandra Carattoli   +4 more
openalex   +1 more source

Targeting the Mapk13‐Tcf1‐Slc7a5 Axis via One‐Carbon Metabolic Regulation to Prevent Chronic Allograft Vasculopathy

Advanced Science, EarlyView.
This study emphasizes the role of the Mapk13‐Tcf1‐Slc7a5‐methionine metabolism axis in stem‐like CD4+ T cells. Moreover, it uncovers the mechanism through which limiting one‐carbon metabolism in CD4+ stem‐like T cells suppresses the tide of chronic allograft vasculopathy, offering potential targets to promote long‐term graft survival.
Wang Yi, Di Wu, Jing Liu, Shi Chen, Liu Song, Bin Xie, Aini Xie, Peixiang Lan, Zhishui Chen   +8 more
wiley   +1 more source

Plasmid-Encoded Multidrug Efflux Pump Conferring Resistance to Olaquindox in Escherichia coli

, 2004
Lars Hestbjerg Hansen, Elsebetta Johannesen, Mette Burmølle, Anders Hay Sørensen, Søren J. Sørensen   +4 more
openalex   +1 more source

Antimicrobial Activity of Cinnamate-eugenol: Synergistic Potential, Evidence of Efflux Pumps and Amino Acid Effects [PDF]

, 2012
D. Rico-Molin, G. Aparicio-O, L. Dorantes-A, H. Rodríguez Hernández   +3 more
openalex   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Evaluation of the Activity of Amino Chalcone Against <i>Staphylococcus</i> Strains Harboring Efflux Pumps. [PDF]

Pharmaceuticals (Basel)
Donato IA, Barbosa CRDS, Bezerra AH, Bezerra SR, Almeida RS, Oliveira-Tintino CDM, Araújo IM, Rodrigues EYS, Oliveira MYC, Cajazeiras FF, Dias JML, Guedes JM, Cristino JHS, Marinho ES, Marinho MM, Santos HSD, Coutinho HDM, Tintino SR, de Menezes IRA, da Cunha FAB.   +19 more
europepmc   +1 more source

Synergetic Relay Between Atomic Hydrogen and Chlorine Radicals Enables Efficient Nitrate‐to‐Nitrogen Gas Conversion

Advanced Science, EarlyView.
Using photoelectrochemical (PEC) deep denitrification technology, a novel synergistic reduction‐oxidation process enables efficient conversion of nitrate (NO3−) to nitrogen (N2), while suppressing key intermediate ammonium (NH4+) and toxic nitrite (NO2−) accumulation.
Yongjie Wang, Ying Tao, Chi Zhang, Shan Hu, Yuxin Shi, Jixing Wang, Jiacheng Zhang, Chen Cheng, Ying Wang, Guisheng Li, Zichao Lian, Dieqing Zhang   +11 more
wiley   +1 more source