Roles of SmeYZ, SbiAB, and SmeDEF Efflux Systems in Iron Homeostasis of Stenotrophomonas maltophilia
Microbiology Spectrum, 2022 Stenotrophomonas maltophilia, a nonfermenting Gram-negative rod, is frequently isolated from the environment and is emerging as a multidrug-resistant global opportunistic pathogen. S.
Chao-Jung Wu +6 more
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Using cellular fitness to map the structure and function of a major facilitator superfamily effluxer. [PDF]
, 2017 The major facilitator superfamily (MFS) effluxers are prominent mediators of antimicrobial resistance. The biochemical characterization of MFS proteins is hindered by their complex membrane environment that makes in vitro biochemical analysis challenging.
Bennett, Matthew R +5 more
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Frontiers in Microbiology, 2015 The era of antibiotics as a cure-all for bacterial infections appears to be coming to an end. The emergence of multidrug resistance in many hospital-associated pathogens has resulted in superbugs that are effectively untreatable.
Karl A Hassan +9 more
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Altered Antibiotic Tolerance in Anaerobic Digesters Acclimated to Triclosan Or Triclocarban [PDF]
, 2016 Bench-scale anaerobic digesters were amended to elevated steady-state concentrations of triclosan (850 mg/kg) and triclocarban (150 mg/kg) using a synthetic feed.
Carey, Daniel Elliott +1 more
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Enhanced efficacy of putative efflux pump inhibitor/antibiotic combination treatments versus MDR strains of Pseudomonas aeruginosa in a Galleria mellonella in vivo infection model [PDF]
, 2015 This work was supported by the University of St Andrews.Objectives: The objectives of this study were to compare the antibiotic susceptibility of Pseudomonas aeruginosa strains with increased efflux pump expression in vitro and in vivo and to use these ...
Adamson, Dougal +2 more
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Vibrio cholerae VexH encodes a multiple drug efflux pump that contributes to the production of cholera toxin and the toxin co-regulated pilus. [PDF]
PLoS ONE, 2012 The resistance-nodulation-division (RND) efflux systems are ubiquitous transporters that function in antimicrobial resistance. Recent studies showed that RND systems were required for virulence factor production in Vibrio cholerae. The V. cholerae genome
Dawn L Taylor +2 more
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Action of cholecalciferol and alpha-tocopherol on Staphylococcus aureus efflux pumps [PDF]
, 2016 Alpha-tocopherol is one the most abundant and biologically active isoforms of vitamin E. This compound is a potent antioxidant and one of most studied isoforms of vitamin E.
Andrade, Jacqueline C. +13 more
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Sodium Benzoate is Associated with Salmonella Typhi Resistant to Chloramphenicol [PDF]
, 2016 Background: There are many factors that govern growth and resistant of Salmonella typhi. A study had reported that the use of sodium benzoate caused antibiotic resistant.
Anand, J. R. (Jay) +4 more
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mBio, 2016 Multidrug efflux pumps provide clinically significant levels of drug resistance in a number of Gram-negative hospital-acquired pathogens. These pathogens frequently carry dozens of genes encoding putative multidrug efflux pumps.
Karl A. Hassan +13 more
doaj +1 more source
A P-type ATPase importer that discriminates between essential and toxic transition metals [PDF]
, 2009 Transition metals, although being essential cofactors in many physiological processes, are toxic at elevated concentrations. Among the membrane-embedded transport proteins that maintain appropriate intracellular levels of transition metals are ATP-driven
A. T. Lee +25 more
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