Results 111 to 120 of about 170,445 (249)
Active efflux systems in the solvent-tolerant bacterium Pseudomonas putida S12 [PDF]
, 2002 The aim of the research presented in this thesis was to study the molecular mechanisms of organic solvent tolerance in Pseudomonas putida S12. This bacterium is capable of growth at saturated solvent concentrations, which are lethal to normal bacteria ...
Kieboom, J.
core
Efflux Pumps in Bacterial Antibiotic Resistance: Mechanisms, Clinical Implications, and Future Directions [PDF]
Due to the discovery of new resistance mechanisms and the decline in effective and high-quality treatments for common pathogenic illnesses, the increased spread of antibiotic resistance across many infectious pathogens has become an increasingly pressing
Mohsin, Sarah Mohammed +2 more
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Advanced Science, EarlyView.Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu +9 more
wiley +1 more source
Functional analysis and NMR studies of multi-drug efflux pumps [PDF]
Efflux pumps play an important role in bacterial multi-drug resistance by actively expelling antibiotics and toxic compounds from the cell. We describe an integrated workflow for the characterisation of inner membrane efflux pumps, consisting of an in ...
Bonev, Boyan B. +5 more
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Experiments on Nonlocal Fluid‐Flow Metamaterials
Advanced Science, EarlyView.A nonlocal fluid‐flow metamaterial composed of standard microfluidic tubes and connectors is designed. Hence, the current of the system at one position depends on the gradient of fluid flow at many other positions, leading to unusual alternating backward and forward laminar flows of water.
Ke Wang, Yi Chen, Martin Wegener
wiley +1 more source
Advanced Science, EarlyView.PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao +8 more
wiley +1 more source
A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus
, 2003 GG918, a synthetic inhibitor of P-glycoprotein-mediated mammalian tumour multidrug resistance, was found to be equipotent to reserpine in enhancing the in vitro activity of norfloxacin and ciprofloxacin against strains of Staphylococcus aureus expressing
Kaatz, Glenn W. +2 more
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, 2020 Susceptibility of reference bacterial strains and mutant strains with impaired efflux pumps to ciprofloxacin and NBTI compounds.
Carla Vignaroli (407543) +12 more
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Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics
Advanced Science, EarlyView.Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan +5 more
wiley +1 more source
Citation: 'efflux pump' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12653 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source