Results 141 to 150 of about 2,541 (192)

Cost-effectiveness of end-game strategies against sleeping sickness across the Democratic Republic of Congo. [PDF]

open access: yesPLoS Negl Trop Dis
Antillon M   +16 more
europepmc   +1 more source

Topical Eflornithine

American Journal of Clinical Dermatology, 2001
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase which is thought to slow hair growth by inhibiting this enzyme in hair follicles. Percutaneous absorption of eflornithine in women with unwanted facial hair (hirsutism) was < 1% when the 15% cream was applied twice daily to a shaved 50 cm2 area of skin under the ...

exaly   +4 more sources

Eflornithine

Pharmaceutisch Weekblad, 1989
Eflornithine (alpha-difluoromethylornithine; DFMO) is a recently developed drug against African trypanosomiasis (sleeping sickness). After a short description of trypanosomiasis and the current treatment, the mechanism of action of eflornithine is discussed, some clinical data is given and attention is paid to recently discovered analogues of ...
A Haemers
exaly   +3 more sources

Eflornithine Plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis

open access: yesNew England Journal of Medicine, 2020
BACKGROUND: The efficacy and safety of combination therapy with eflornithine and sulindac, as compared with either drug alone, in delaying disease progression in patients with familial adenomatous polyposis are unknown. METHODS: We evaluated the efficacy
Steven Gallinger   +2 more
exaly   +3 more sources

Eflornithine

Journal of the Dermatology Nurses' Association, 2021
ABSTRACT Drugs are substances that exert effects in the body in order to alter an existing physiological or biochemical process. There are several methods of administering drugs, including the use of creams, ointments, liquids, skin patches, capsules, and injections.
Ana Carolina Chen, Janiene D. Luke
openaire   +1 more source

Population Pharmacokinetic Modeling and Deconvolution of Enantioselective Absorption of Eflornithine in the Rat

open access: yesJournal of Pharmacokinetics and Pharmacodynamics, 2013
Enantioselective pharmacokinetics and absorption of eflornithine in the rat was investigated using population pharmacokinetic modeling and a modified deconvolution method.
Michael Ashton   +2 more
exaly   +2 more sources

Home - About - Disclaimer - Privacy