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Eflornithine for the treatment of human African trypanosomiasis
Parasitology Research, 2003Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. The most commonly used dosage regimen for the treatment of T. b.
Burri C, Brun R
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Treatment of Recurrent Gliomas With Eflornithine
JNCI Journal of the National Cancer Institute, 1992Oral eflornithine in combination with intravenous mitoguazone (methylbisguanylhydrazone) has shown activity against recurrent anaplastic gliomas. Eflornithine alone, however, has not been evaluated against recurrent gliomas.This study compared the antitumor activity of oral eflornithine with that of oral eflornithine combined with intravenous ...
V A, Levin +5 more
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Eflornithine (Iwilfin) for High-Risk Neuroblastoma
The Medical Letter on Drugs and TherapeuticsEflornithine (Iwilfin – US WorldMeds), an oral ornithine decarboxylase inhibitor, has been approved by the FDA to reduce the risk of relapse in children and with high-risk neuroblastoma who had at least a partial response to prior multiagent, multimodality therapy, including anti-GD2 immunotherapy.
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Vaniqa--eflornithine 13.9% cream.
Skin therapy letter, 2001Eflornithine HCl 13.9% cream is the first topical prescription treatment to be approved by the US FDA for the reduction of unwanted facial hair in women. It irreversibly inhibits ornithine decarboxylase (ODC), an enzyme that catalyzes the rate-limiting step for follicular polyamine synthesis, which is necessary for hair growth.
J, Shapiro, H, Lui
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Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2021
Mohamed A Abdel-Lateef +1 more
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Mohamed A Abdel-Lateef +1 more
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