Results 101 to 110 of about 2,541 (192)

Changes in metabolite abundance (relative intensity) induced by 5 hours of eflornithine, nifurtimox and NECT treatment expressed relative to untreated levels.

, 2012
Changes in metabolite abundance (relative intensity) induced by 5 hours of eflornithine, nifurtimox and NECT treatment expressed relative to untreated levels.
Isabel M. Vincent (167717), Debra J. Woods (167740), Richard J. S. Burchmore (167742), Darren J. Creek (167726), Karl Burgess (167732), Michael P. Barrett (167748)   +5 more
core   +1 more source

Safety and Efficacy of Eflornithine in Patients with Gastric Precancerous Lesions: A Double-Blinded, Randomized Clinical Trial. [PDF]

Cancer Prev Res (Phila)
Morgan DR, Dominguez RL, Norwood DA, Montalvan-Sanchez EE, Piazuelo MB, Rodriguez-Murillo A, Delgado AG, Hernandez-Marrero J, Gonzalez-Pons M, Beasley TM, Cruz-Correa M, Wilson KT.   +11 more
europepmc   +1 more source

STELLAR: Phase III, Randomized, Open-Label Study of Eflornithine Plus Lomustine Versus Lomustine Alone in Patients With Recurrent Grade 3 Astrocytoma. [PDF]

J Clin Oncol
Colman H, Lombardi G, Wong ET, Walbert T, Eoli M, Lassman AB, Peereboom DM, Kizilbash SH, Kamiya-Matsuoka C, Pitz MW, Strowd RE, Desjardins A, Kumthekar P, Mason W, Pellerino A, Soffietti R, Butowski N, Forsyth PA, Hamza MA, Hau P, Lallana E, Nabors B, Piccioni D, Uhlmann EJ, Welsh LC, Wen PY, Dietrich J, Wang C, Levin VA.   +28 more
europepmc   +1 more source

Targeted Therapies in Neuroblastoma: A History and a View to the Future. [PDF]

Cancers (Basel)
Shah N.
europepmc   +1 more source

Single-cell Sequencing and Machine Learning Identify Amino Acid Metabolism-related Biomarkers and Regulatory Mechanisms in Diabetic Foot Ulcers. [PDF]

Endocr Metab Immune Disord Drug Targets
Wang W, Xia Z, Wang Y, Wang F, Han F.
europepmc   +1 more source

Spermine Synthase at the Polyamine-Redox Interface: Mechanistic Evidence from Snyder-Robinson Syndrome and Cancer. [PDF]

Antioxidants (Basel)
Lin Z, Lin Y, Li M, Zhan S, Xu Q, Yu F.
europepmc   +1 more source

Combination of Intense Pulsed Light and Topical Eflornithine Therapy Versus Intense Pulsed Light Alone in the Treatment of Idiopathic Facial Hirsutism: A Randomized Controlled Trial. [PDF]

Cureus
Nawaz MU, Baig MB, Shahid SM, Nawaz MH, Inayat S, Dawood M.   +5 more
europepmc   +1 more source

Use of real-world evidence in the U.S. Food and Drug Administration and the European Medicines Agency approvals of oncology products supported by single-arm trials (2022-2025). [PDF]

Oncologist
Su L, Chen L, Mamtani R, Betigeri S, Hubbard R, Burcu M.   +5 more
europepmc   +1 more source

Tislelizumab combined with Anti-GD2 antibody-based chemoimmunotherapy for pediatric relapsed/refractory high-risk neuroblastoma: a two-Case Report. [PDF]

Front Pharmacol
Zhang T, Liao X, Li Y, Yang J, Shao J, Zhang H, Jiang S.   +6 more
europepmc   +1 more source

Mono-, di- and trisubstituted derivatives of eflornithine: synthesis for in vivo delivery of DL-alpha-difluoromethylornithine in plasma

, 2011
The aim of this study was to synthesize a series of mono-, di- and trisubstituted derivatives of the human African trypanosomiasis drug eflornithine (α-difluoro-methylornithine, DMFO, CAS 70052-12-9) to determine their partition coefficients, and to ...
Cloete, TT, Vodnala, SK, Rottenberg, ME, Johansson, Carl C.,, Breytenbach, JC, N'Da, DD, Ashton, Michael,   +6 more
core