Results 151 to 160 of about 3,610 (188)

Eflornithine

Journal of the Dermatology Nurses' Association, 2021
ABSTRACT Drugs are substances that exert effects in the body in order to alter an existing physiological or biochemical process. There are several methods of administering drugs, including the use of creams, ointments, liquids, skin patches, capsules, and injections.
Ana Carolina Chen, Janiene D. Luke
openaire   +1 more source

Topical Eflornithine

American Journal of Clinical Dermatology, 2001
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase which is thought to slow hair growth by inhibiting this enzyme in hair follicles. Percutaneous absorption of eflornithine in women with unwanted facial hair (hirsutism) was < 1% when the 15% cream was applied twice daily to a shaved 50 cm2 area of skin under the ...
J A, Balfour, K, McClellan
openaire   +3 more sources

Eflornithine

Pharmaceutisch Weekblad, 1989
Eflornithine (alpha-difluoromethylornithine; DFMO) is a recently developed drug against African trypanosomiasis (sleeping sickness). After a short description of trypanosomiasis and the current treatment, the mechanism of action of eflornithine is discussed, some clinical data is given and attention is paid to recently discovered analogues of ...
I, Van Bogaert, A, Haemers
openaire   +2 more sources

Treatment of Recurrent Gliomas With Eflornithine

JNCI Journal of the National Cancer Institute, 1992
Oral eflornithine in combination with intravenous mitoguazone (methylbisguanylhydrazone) has shown activity against recurrent anaplastic gliomas. Eflornithine alone, however, has not been evaluated against recurrent gliomas.This study compared the antitumor activity of oral eflornithine with that of oral eflornithine combined with intravenous ...
V A, Levin   +5 more
openaire   +2 more sources

Eflornithine for the treatment of human African trypanosomiasis

Parasitology Research, 2003
Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. The most commonly used dosage regimen for the treatment of T. b.
Christian, Burri, Reto, Brun
openaire   +2 more sources

Late-Stage African Trypanosomiasis and Eflornithine

Annals of Internal Medicine, 1986
Excerpt To the editor: Human trypanosomiasis is a major public health problem in many African countries. At present, there is alarm at the recrudescence of this disease in its historical habitats.
CESARE DI BARI   +4 more
openaire   +1 more source

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