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Does ▼eflornithine help women face hirsutism?
Drug and Therapeutics Bulletin, 2007Many women develop male-pattern facial hair (facial hirsutism), which can be distressing and difficult to treat. ▼Eflornithine (Vaniqa – Shire) is a topical cream available only on prescription for treating women with facial hirsutism. Promotional material claims that the treatment “slows facial hair growth – grows her confidence”.
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Vaniqa--eflornithine 13.9% cream.
Skin therapy letter, 2001Eflornithine HCl 13.9% cream is the first topical prescription treatment to be approved by the US FDA for the reduction of unwanted facial hair in women. It irreversibly inhibits ornithine decarboxylase (ODC), an enzyme that catalyzes the rate-limiting step for follicular polyamine synthesis, which is necessary for hair growth.
J, Shapiro, H, Lui
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Eflornithine (Iwilfin) for High-Risk Neuroblastoma
The Medical Letter on Drugs and TherapeuticsEflornithine (Iwilfin – US WorldMeds), an oral ornithine decarboxylase inhibitor, has been approved by the FDA to reduce the risk of relapse in children and with high-risk neuroblastoma who had at least a partial response to prior multiagent, multimodality therapy, including anti-GD2 immunotherapy.
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