Results 91 to 100 of about 1,172 (162)
Supplementary Figure 4 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR [PDF]
, 2013 PDF File - 438K, HER2 : EFTUD2 copy number ratio in validation cohort.
Heidrun Gevensleben (3308331) +8 more
core +1 more source
Advanced Science, Volume 12, Issue 13, April 3, 2025.HCETSR, derived from tRNA‐Glu/TTC, binds to SPTBN1, promoting the dissociation of SPTBN1 from the catenin complex and facilitating the translocation of the catenin complex from the cell membrane to the nucleus. Meanwhile, HCETSR reduces proteasomal degradation of β‐catenin and synthesis of nascent β‐catenin.
Tao Rui +13 more
wiley +1 more source
Disease modelling of core pre-mRNA splicing factor haploinsufficiency [PDF]
, 2019 The craniofacial disorder Mandibulofacial Dysostosis Guion-Almedia type is caused by haploinsufficiency of the U5 snRNP gene EFTUD2/SNU114. However, it is unclear how reduced expression of this core pre-mRNA splicing factor leads to craniofacial defects.
Thomas, Huw +9 more
core +1 more source
Advanced Science, Volume 12, Issue 12, March 27, 2025.Targeting mesothelin (MSLN) improved neoantigen vaccine efficacy in pancreatic cancer by reducing apCAFs, which disrupted the conversion of naive CD4+ T cells into Tregs and enhanced the infiltration of IFN‐γ+CD4+ and GZMK+CD8+ T cells. This combination strengthened neoantigen‐specific T cell response to overcome the immunosuppressive tumor ...
Zhixiong Cai +11 more
wiley +1 more source
Supplementary Figure 6 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR [PDF]
, 2013 PDF File - 694K, Comparison between EFTUD2 and UBBP4 reference probes on patient plasma samples.
Heidrun Gevensleben (3308331) +8 more
core +1 more source
Understanding GEMIN5 Interactions: From Structural and Functional Insights to Selective Translation
WIREs RNA, Volume 16, Issue 2, March/April 2025.GEMIN5 structural domains. Overview of GEMIN5's role in snRNP assembly and translation regulatory events. ABSTRACT GEMIN5 is a predominantly cytoplasmic protein, initially identified as a member of the survival of motor neurons (SMN) complex. In addition, this abundant protein modulates diverse aspects of RNA‐dependent processes, executing its ...
Encarnacion Martinez‐Salas +2 more
wiley +1 more source
LncRNA DGUOK-AS1 Promotes Bladder Cancer Progression by Enhancing EFTUD2 Stability
Cancer Research and TreatmentLong noncoding RNAs (lncRNAs) are increasingly being recognized to play important roles in cancer pathogenesis. However, the functional mechanisms of most lncRNAs remain poorly understood.RNA sequencing was performed to identify differentially expressed lncRNAs between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).
Wenwei, Ying +3 more
openaire +2 more sources
A Brief Analysis on Clinical Severity of Mandibulofacial Dysostosis Guion-Almeida Type [PDF]
, 2022 Objective: Genetic variants in EFTUD2 were proven to influence variable phenotypic expressivity in mandibulofacial dysostosis Guion-Almeida type (MFDGA) or mandibulofacial dysostosis with microcephaly (MFDM).
Istifiani, Lola Ayu +14 more
core
Silencing U5 snRNP components enhances DENV replication. [PDF]
, 2016 (A) Reporter DENV replication in A549 cells transfected with siRNA directed to spliceosomal proteins (CD2BP2, DDX23, SNRNP40, PRPF8, EFTUD2, SNRNP200 or SF3A2). An infectious DENV carrying the luciferase gene was used. Three controls were included: a non-
Guillermo Risso (438757) +12 more
core +1 more source
Table_1_Evaluation of RNA Blood Biomarkers in the Parkinson’s Disease Biomarkers Program.DOC [PDF]
, 2018 There is a high misdiagnosis rate between Parkinson’s disease (PD) and atypical parkinsonian disorders (APD), such as progressive supranuclear palsy (PSP), the second most common parkinsonian syndrome. In our earlier studies, we identified and replicated
Virginie Bottero (253760) +2 more
core +1 more source