Results 31 to 40 of about 641 (114)
Preconditioning with Ginkgo biloba (EGb 761®) provides neuroprotection through HO1 and CRMP2
Ginkgo biloba/EGb 761® (EGb 761) is a popular and standardized natural extract used worldwide for the treatment of many ailments. Although EGb 761 is purported to have a plethora of benefits, here, we were interested to study the neuroprotective ...
Shadia E. Nada, Zahoor A. Shah
doaj +1 more source
Gravitational Collapse in the EGB Gravity
27 pages, 25 figures, several typos corrected, discussion ...
Chatterjee, Ayan +2 more
openaire +2 more sources
A 500‐kyr Pluvial Interval Triggered Lacustrine Carbon Burial in Late Cretaceous East Asia
Abstract The early Late Cretaceous hothouse was featured by intense storms and a prevailing monsoon climate, yet direct evidence for regional extreme precipitation events is rare. Here, we reconstruct local weathering and hydrological processes using magnesium and strontium isotopes (δ26Mg and 87Sr/86Sr) from lacustrine dolostones in the Upper ...
Yuke Liu +6 more
wiley +1 more source
Electrocardiographic effects produced by Ginkgo biloba extract (EGb) and by ginkgolides A (GA) and B (GB), and bilobalide (BB) were investigated in guinea pig heart mounted in Langendorff apparatus (Tyrode, 34 ± 0.1 ºC, 95% O2, 5% CO2 ...
A.C.O. Santos +6 more
doaj +1 more source
Cannabidiol (CBD) exhibits increased reactivity, stronger CB1 receptor binding, and enhanced cytotoxicity against A431 squamous carcinoma cells compared to 5‐fluorouracil (5‐FU). Integrated DFT, molecular docking, and experimental analyses demonstrate CBD's improved stability and binding affinity, highlighting its potential as an alternative ...
Andrea Jess Josiah +5 more
wiley +1 more source
ABSTRACT The main protease (Mpro) of severe acute respiratory syndrome coronavirus 2 remains a primary target for antiviral drug discovery. In this study, an integrated computational workflow—comprising molecular docking, triplicate 200 ns molecular dynamics (MD) simulations, Molecular Mechanics–Generalized Born Surface Area (MM/GBSA) binding free ...
Renato Araújo da Costa +8 more
wiley +1 more source
Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model
Background Metastasis refers to the spread of a primary tumor cell from the primary site to other locations in the body and it is generally associated with the severity of a tumor.
Huan Wang +6 more
doaj +1 more source
Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram +6 more
wiley +1 more source
A radiating star in Einstein-Gauss-Bonnet gravity
We generate a radiating star in Einstein-Gauss-Bonnet (EGB) gravity for spacetime dimension N=5 and a shear-free geometry. The temporal boundary condition contains curvature corrections from the Lovelock tensor and reduces to the general relativity limit.
Sunil D. Maharaj +3 more
doaj +1 more source
Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma
ABSTRACT Oncolytic viruses, specifically Sindbis virus (SINV), combined with cytokines show promising results in slowing glioma progression, but a quantitative understanding of their effects remains limited. In this study, we use an ordinary differential equation (ODE) model to examine the effect of adding cytokines to oncolytic SINV therapy.
Shriya Makam, Hana M. Dobrovolny
wiley +1 more source

