MDCK-Adaptive Mutation of A169S Changes Glycosylation Pattern of Hemagglutinin and Enhances MDCK-Based H7N9 Vaccine Virus Production without Loss of Antigenicity and Immunogenicity [PDF]
VaccinesThe adaptation of egg-derived H7N9 candidate vaccine virus (CVV) in the mammalian cell line is an approach to developing a high-growth virus strain for the mass production of vaccine manufacturing.
Po-Ling Chen +8 more
doaj +2 more sources
Vaccines, 2022 Seasonal Influenza H3N2 virus poses a great threat to public health, but its vaccine efficacy remains suboptimal. One critical step in influenza vaccine production is the viral passage in embryonated eggs. Recently, the strength of egg passage adaptation
Hui Chen +13 more
doaj +1 more source
آنالیز توالی ژن S1 سویه های واکسینال برونشیت عفونی طیور(H120 & H52) و ارزیابی تاثیر پاساژهای متوالی در تخم مرغ جنین دار بر آنها [PDF]
Archives of Razi Institute, 2016 بیماری برونشیت عفونی طیور(IB) یکی از بیماریهای حاد و بشدت واگیردار طیور است که عمدتاً موجب ابتلاء دستگاه تنفس میشود. وجود تعداد زیاد سویهها و سروتیپهای ویروس عامل بیماری که قادر به ایجاد ایمنیت متقاطع بر علیه یکدیگر نیستند مهمترین مانع کسب نتایج ...
مهران بخشش +3 more
doaj +1 more source
Comparison of endocytosis pathways of Duck Tembusu virus in BHK-21 and duck embryo fibroblasts
Poultry Science, 2023 : The Duck Tembusu virus (DTMUV) is a zoonotic flavivirus characterized by nonsuppurative encephalitis and decreasing egg production that has adversely affected the poultry industry.
Xuemei Xian +3 more
doaj +1 more source
Killifish eggs can disperse via gut passage through waterfowl [PDF]
Ecology, 2019 Peer ...
Silva, G. G. +9 more
openaire +3 more sources
Low 2012-13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses. [PDF]
PLoS ONE, 2014 Influenza vaccine effectiveness (VE) is generally interpreted in the context of vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to explain reduced protection.
Danuta M Skowronski +16 more
doaj +1 more source
Open Veterinary Journal, 2023 Background: Mycoplasma synoviae is an important poultry pathogen causing heavy economic losses Worldwide. Subclinical persistence of this pathogen is the major issue to control its prevalence. Aim: This study aimed to determine the molecular and cross
Atta Ur Rehman +8 more
doaj +1 more source
Prevalence and molecular characterization of infectious bronchitis virus isolated from chicken in Bangladesh [PDF]
Veterinary World, 2019 Aim: The present study was aimed to determine the prevalence of infectious bronchitis virus (IBV) as well as virus isolation, identification, and molecular characterization of various strains circulating in Bangladesh.
Zafar Ahmed Bhuiyan +4 more
doaj +1 more source
Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus [PDF]
Viruses, 2022 Seasonal H3N2 influenza evolves rapidly, leading to an extremely poor vaccine efficacy. Substitutions employed during vaccine production using embryonated eggs (i.e., egg passage adaptation) contribute to the poor vaccine efficacy (VE), but the evolutionary mechanism remains elusive. Using an unprecedented number of hemagglutinin sequences (n = 89,853),
Yunsong Liu +7 more
openaire +5 more sources
Passage of Meloidogyne Eggs in Human Stool: Forgotten, but Not Gone [PDF]
Journal of Clinical Microbiology, 2015 Recently, we were involved in a project to train staff from the Atoifi Adventist Hospital (AAH) in East Kwaio, Malaita, Solomon Islands, in applied research and laboratory methods. The project, run by AAH, included the performance of a cross-sectional survey for soil-transmitted helminths in ...
Bradbury, Richard S., Speare, Rick.
openaire +3 more sources