Results 61 to 70 of about 8,274 (166)

Serum biomarkers of patients with EGPA based on prednisone usage at time of study visit.

, 2015
Data are shown as median (range in parenthesis); EGPA: eosinophilic granulomatosis with polyangiitis (Churg-Strauss); LR, Logistic regression analysis as described in Materials and Methods; MWU, Mann Whitney U test; n, number of visits; pred ...
David Cuthbertson (188652), Peter A. Merkel (188721), Simon Carette (188665), Bastian Oppl (713196), Christian Dejaco (12618), Nader Khalidi (713199), Gary Hoffman (713198), Paul Monach (713197), Jochen Zwerina (11574), Carol Langford (713201), Steven Ytterberg (713203), Curry Koening (713200), Philip Seo (188695), Ulrich Specks (972), Kathleen McKinnon-Maksimowicz (713202)   +14 more
core   +1 more source

Once upon a time: the curious case of a backward story of EGPA [PDF]

Exploration of Asthma & Allergy
A high percentage of patients with severe asthma also suffer from nasal polyposis, with dupilumab, an anti-IL-4R antibody both diseases can be treated due to its role in type 2 (T2) inflammation.
Diego Bagnasco, Benedetta Bondi, Veronica Capuano, Frank Rikki Mauritz Canevari, Cesare De Tomaso, Sara Fedele, Vincenzo Milano, Marcello Mincarini, Michela Robbiano, Melania Bertolini, Fulvio Braido   +10 more
doaj   +1 more source

Real‐World Use of Avacopan in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Early and Long‐Term Clinical, Renal, and Patient‐Reported Outcomes in an Italian Rheumatology–Nephrology Network

ACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective Complement activation, particularly through the C5a–C5a receptor axis, plays a pivotal role in the pathogenesis of antineutrophil cytoplasmic antibody–associated vasculitis (AAV) and may represent an important therapeutic target. Avacopan, an oral C5a receptor antagonist, was the first therapy targeting this pathway to enter in clinical ...
Luca Quartuccio, Elena Treppo, Miriam Isola, Maria De Martino, Chiara Marvisi, Luca Iorio, Alessandra Milanesi, Luca Moroni, Edoardo Conticini, Stefania Affatato, Maria Letizia Urban, Enrico Tombetti, Fabio Barone, Pasquale Esposito, Florenzo Iannone, Valentina Binda, Giuseppe Castellano, Corrado Murtas, Lida Tartaglione, Francesco Delle Monache, Amelia Rigon, Maria Chiara Panini, Marco Allinovi, Augusto Vaglio, Bruno Frediani, Paolo Delvino, Sara Monti, Roberto Padoan, Carlomaurizio Montecucco, Lorenzo Dagna, Giacomo Emmi, Federico Alberici, Carlo Salvarani, on behalf of the Italian Society of Rheumatology (Vasculitis and Polymyalgia Rheumatica Study Group)   +33 more
wiley   +1 more source

UpToDate on eosinophils [PDF]

Exploration of Asthma & Allergy
This review describes the eosinophil journey through the various physiological and pathophysiological phases, from production, maturation, and activation by chemokines and cytokines [especially eotaxin, interleukin (IL)-5, IL-3, and granulocyte ...
Mario Di Gioacchino, Diego Bagnasco, Fulvio Braido, Federica Buta, Pasquale Caponnetto, Roberto Giovanni Carbone, Mario Cazzola, Willem van de Veen, Camilla De Vitis, Linhong Deng, Nelson Rosario Filho, Eva Rebelo Gomes, Giuseppe Guida, Dichapong Kanjanawasee, Nathachit Limjunyawong, Mauro Maniscalco, Mário Morais-Almeida, Giuseppe Murdaca, Jayoung Oh, Giovanni Paoletti, Vincenzo Patella, Ana Margarida Pereira, Graziella Chiara Prezzavento, Francesco Puppo, Chae-Seo Rhee, Erminia Ridolo, Matija Rijavec, Nikoletta Rovina, Franziska Roth-Walter, Pongsakorn Tantilipikorn, Arzu Yorgancıoğlu, Garry Michael Walsh, Torsten Zuberbier, Giorgio Walter Canonica   +33 more
doaj   +1 more source

Coronary artery dissection and Myocarditis caused by Eosinophilic granulomatosis with polyangiitis (EGPA): A case report

, 2023
Eosinophilic granulomatosis with polyangiitis (EGPA) also referred to as Churg-Strauss syndrome is a rare vasculitis of the small to medium vessels.
Vidhyalakshmy Vivek, Esraa Hassan, Khan, Syed A, Trivedi, Setu, Surani, Salim, Anwar Khedr, Korsapati, Aishwarya R, Jain, Shika, Setu Trivedi, Patnaik, Harsha, Noura Attallah, Xu, Qiping, Korsapati, Hariprasad R, Mikael Mir, Nitesh Kumar Jain, Khedr, Anwar, Salim Surani, Jama, Abbas B, Attallah, Noura, Namratha Seetharam Meda, Ali, Syed, Sri Usha Jeevani Obulareddy, Harsha Patnaik, Mir, Mikael, Aishwarya Reddy Korsapati, Bawaadam, Hasnain, Sumeet Yadav, Hariprasad Reddy Korsapati, Meda, Namratha S, Jeevani Obulareddy, Sri U, Hassan, Esraa, Shika Jain, Jain, Nitesh K, Rauf, Ibtisam, Qiping Xu, Ibtisam Rauf, Hasnain Bawaadam, Vivek, Vidhyalakshmy, Abbas B. Jama, Yadav, Sumeet, Syed Ali, Syed Anjum Khan, Korsapati, Aishwarya Reddy, Khan, Syed Anjum, Meda, Namratha Seetharam, Jain, Nitesh Kumar, Obulareddy, Sri Usha Jeevani, Jama, Abbas B., Korsapati, Hariprasad Reddy   +48 more
core   +1 more source

Clinical Characteristics of Peripheral Neuropathy in Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Single-Center Study in China

Journal of Immunology Research, 2020
Objective. To investigate clinical features, independent associated factors, treatment, and outcome of patients with peripheral neuropathy (PN) in eosinophilic granulomatosis with polyangiitis (EGPA). Methods. We retrospectively analyzed clinical data of
Zhaocui Zhang, Suying Liu, Ling Guo, Li Wang, Qingjun Wu, Wenjie Zheng, Yong Hou, Xinping Tian, Xiaofeng Zeng, Fengchun Zhang   +9 more
doaj   +1 more source

Independent Agencies, Regulation‐Compliant Citizens? Evidence From a Survey Experiment on Vaccine Authorization in the EU

Regulation &Governance, Volume 20, Issue 4, Page 2315-2332, October 2026.
ABSTRACT The effectiveness of regulatory policy in many areas is contingent on citizens adhering to the scientific advice of regulatory bodies. This in turn depends on whether they perceive this advice as credible. One of the biggest threats to regulatory credibility is the concern that regulatory policy can be tainted by short‐term political interests.
Benjamin Leidorf‐Tidå, Saar Alon‐Barkat, Madalina Busuioc, Thijs de Boer   +3 more
wiley   +1 more source

Airway immune profiles and therapeutic implications of IGF1 in eosinophilic granulomatosis with polyangiitis

Nature Communications
Eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma (SEA) share a Type 2 (T2) inflammatory signature but exhibit distinct pathophysiology.
Cong Dong, Bingtai Lu, Changhao Zhong, Changxing Ou, Xiaojing Yang, Lingwei Wang, Xiaoyu Zuo, Lingna Xue, Chenyang Lu, Shang Wang, Junjie Wen, Jianjuan Ma, Zhenan Deng, Yiyi Liu, Liuheyi Ma, Ming Liu, Andrew M. Lew, Manali Mukherjee, Parameswaran Nair, Nanshan Zhong, Rongchang Chen, Zhanghua Chen, Yuxia Zhang, Qingling Zhang   +23 more
doaj   +1 more source

Algorithms in Allergy: Diagnosis of Hypereosinophilic Syndromes, 2026 Update

Allergy, EarlyView.
Guillaume Lefèvre, Florence Roufosse, Giacomo Emmi, Andreas Reiter, Emmanuel Ledoult, Jean‐Emmanuel Kahn   +5 more
wiley   +1 more source

A new cytological approach to improve the final diagnosis of Eosinophilic Granulomatosis with Polyangiitis (EGPA)

, 2017
Introduction: Eosinophilic granulomatosis with polyangiitis (EGPA) is an uncommon systemic necrotizing vasculitis that affects small to medium sized vessels and is associated with severe asthma, allergic rhinitis, nasal polyposis and blood and tissue ...
AGOSTINI, CARLO, Schiavon, F, Padoan, R, Zanotti, C, MARIONI, GINO, Brescia, G, Caputo, I, Neri, R, Cinetto, F, CANGIANO, DANIELA   +9 more
core   +1 more source