Results 21 to 30 of about 357 (108)

Genomic features of humoral immunity support tolerance model in Egyptian rousette bats [PDF]

Cell Reports, 2021
Summary: Bats asymptomatically harbor many viruses that can cause severe human diseases. The Egyptian rousette bat (ERB) is the only known reservoir for Marburgviruses and Sosuga virus, making it an exceptional animal model to study antiviral mechanisms ...
Peter A. Larson, Maggie L. Bartlett, Karla Garcia, Joseph Chitty, Anne Balkema-Buschmann, Jonathan Towner, Jeffrey Kugelman, Gustavo Palacios, Mariano Sanchez-Lockhart   +8 more
doaj   +3 more sources

Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera [PDF]

Viruses, 2015
The Egyptian rousette bat (Rousettus aegyptiacus) is a natural reservoir for marburgviruses and a consistent source of virus spillover to humans. Cumulative evidence suggests various bat species may also transmit ebolaviruses.
Megan E.B. Jones, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, Sherif R. Zaki, Stuart T. Nichol, Jonathan S. Towner   +6 more
doaj   +3 more sources

Unique Features of Immunity within the Immunoglobulin Heavy Chain Locus of Egyptian Rousette Bats [PDF]

Proceedings, 2020
Marburg virus (MARV) presents with a hemorrhagic fever in primates but asymptomatically in its known reservoir, the Egyptian rousette bat (Rousettus aegyptiacus, ERB). Understanding the biological mechanisms that explain these differential outcomes could
Maggie L. Bartlett, Peter A. Larson, Mariano Sanchez-Lockhart, Gustavo Palacios   +3 more
doaj   +2 more sources

Variations in small-scale movements of, Rousettus aegyptiacus, a Marburg virus reservoir across a seasonal gradient [PDF]

Frontiers in Zoology, 2023
Background Bats are increasingly being recognized as important hosts for viruses, some of which are zoonotic and carry the potential for spillover within human and livestock populations.
Matthew R. Wood, J. Low de Vries, Jonathan H. Epstein, Wanda Markotter   +3 more
doaj   +2 more sources

The Unique Immune System of Bats: An Evolutionary Analysis and Bibliometric Study. [PDF]

Ecol Evol
Through the evolutionary and bibliometric analyses, this study identified several critical immune genes and signaling pathways related to bat immunity. Currently, research on the immune system of bats primarily focuses on the themes of “efficient antiviral responses” and “inflammation suppression.” ABSTRACT Bats exhibit a greater capacity to tolerate ...
Li R, Zhao W, Chen A, Wu Z, De G.
europepmc   +2 more sources

Histopathologic and Immunohistochemical Evaluation of Induced Lesions, Tissue Tropism and Host Responses following Experimental Infection of Egyptian Rousette Bats (Rousettus aegyptiacus) with the Zoonotic Paramyxovirus, Sosuga Virus [PDF]

Viruses, 2022
Ecological and experimental infection studies have identified Egyptian rousette bats (ERBs; Rousettus aegyptiacus: family Pteropodidae) as a reservoir host for the zoonotic rubula-like paramyxovirus Sosuga virus (SOSV). A serial sacrifice study of colony-
Shannon G. M. Kirejczyk, Brian R. Amman, Amy J. Schuh, Tara K. Sealy, César G. Albariño, Jian Zhang, Corrie C. Brown, Jonathan S. Towner   +7 more
doaj   +2 more sources

Landscape and age dynamics of immune cells in the Egyptian rousette bat [PDF]

Cell Reports, 2022
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Virginia Friedrichs, Christophe Toussaint, Alexander Schäfer, Melanie Rissmann, Oliver Dietrich, Thomas C. Mettenleiter, Gang Pei, Anne Balkema‐Buschmann, Antoine‐Emmanuel Saliba, Anca Dorhoi   +9 more
openalex   +3 more sources

Modeling natural coinfection in a bat reservoir shows modulation of Marburg virus shedding and spillover potential. [PDF]

PLoS Pathogens
The Egyptian rousette bat (ERB) is a natural reservoir for Marburg virus (MARV; family Filoviridae), a putative reservoir for Sosuga virus (SOSV; family Paramyxoviridae), and a vertebrate reservoir for Kasokero virus (KASV; family Orthonairoviridae ...
Amy J Schuh, Brian R Amman, Jonathan C Guito, James C Graziano, Tara K Sealy, Jonathan S Towner   +5 more
doaj   +2 more sources

The latest advancements in Sosuga virus (SOSV) research [PDF]

Frontiers in Microbiology
The last 60 years have seen the emergence of several zoonotic viruses, some of which originate from bats. Among these are Nipah virus, Marburg virus and Ebola viruses, which have high case fatality rates, and pose significant public health risks. In 2012,
Nathan M. Markarian, Levon Abrahamyan
doaj   +2 more sources

Ephrin B1 and B2 Mediate Cedar Virus Entry into Egyptian Fruit Bat Cells [PDF]

Viruses
Cedar virus (CedV), closely related to the Hendra and Nipah viruses, is a novel Henipavirus that was originally isolated from flying foxes in Australia in 2012. Although its glycoprotein G exhibits relatively low sequence similarity with its counterparts
Lea Lenhard, Martin Müller, Sandra Diederich, Lisa Loerzer, Virginia Friedrichs, Bernd Köllner, Stefan Finke, Anca Dorhoi, Gang Pei   +8 more
doaj   +2 more sources