Host membrane lipids are trafficked to membranes of intravacuolar bacterium Ehrlichia chaffeensis. [PDF]
Proc Natl Acad Sci U S A, 2020 Significance Biological membranes are essential for life. Although bacteria and eukaryotic cells have evolved to produce membranes of different compositions, several bacterial pathogens can hijack and utilize host-synthesized membrane lipids.
Lin M +5 more
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Multi-Locus Sequence Typing of Ehrlichia chaffeensis Reveals Extensive Genotypic Variation across the United States. [PDF]
Am J Trop Med Hyg, 2021 Ehrlichia chaffeensis causes human monocytic ehrlichiosis, and its principal vector is the Amblyomma americanum tick. The most frequently identified cases of ehrlichiosis come from the southeastern and south central states of the United States.
Zambrano ML, Paddock CD, Karpathy SE.
europepmc +2 more sources
Evidence of Ehrlichia chaffeensis in Argentina through molecular detection in marsh deer (Blastocerus dichotomus) [PDF]
International Journal for Parasitology: Parasites and Wildlife, 2019 Vector-borne pathogens are responsible for serious emerging diseases and have been widely described in wildlife. Ehrlichia chaffeensis causes the zoonotic “monocytic ehrlichiosis” in humans, is transmitted by the tick Amblyomma americanum and its ...
Eliana C. Guillemi +3 more
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Ehrlichia chaffeensis in Child, Venezuela
Emerging Infectious Diseases, 2008 To the Editor: Human monocytic ehrlichiosis is a tick-borne infectious disease caused by Ehrlichia chaffeensis (1). Serologic studies have indicated E. chaffeensis infection in Latin American countries: Venezuela (2), Mexico (3), Argentina (4), Chile (5), and Brazil (6). However, no molecular evidence for E. chaffeensis has been reported.
María C. Martínez +7 more
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Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection. [PDF]
PLoS Pathog, 2020 Ehrlichia chaffeensis (E. chaffeensis) exploits evolutionarily conserved Notch and Wnt host cell signaling pathways to downregulate innate immune host defenses and promote infection. The multifunctional E.
Wang JY +5 more
europepmc +2 more sources
Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with In Vivo Infection Assessment. [PDF]
Infect Immun, 2020 Ehrlichia chaffeensis, a tick-transmitted obligate intracellular rickettsial agent, causes human monocytic ehrlichiosis. In recent reports, we described substantial advances in developing random and targeted gene disruption methods to investigate the ...
Wang Y +10 more
europepmc +2 more sources
Anaplasmataceae closely related to Ehrlichia chaffeensis and Neorickettsia helminthoeca from birds in Central Europe, Hungary. [PDF]
Antonie Van Leeuwenhoek, 2020 Increasing amount of data attest that (in the context of vector-borne infections) birds are not only important as hosts of blood-sucking arthropod vectors, but also as reservoirs of vector-borne pathogens. From 2015 to 2019 cadavers of 100 birds (from 45
Hornok S +10 more
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Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes. [PDF]
NPJ Vaccines, 2020 Immunomolecular characterization of Ehrlichia chaffeensis (E. ch.) and E. canis (E. ca.) has defined protein orthologs, including tandem repeat proteins (TRPs) that have immunodominant linear antibody epitopes.
Luo T +4 more
europepmc +2 more sources
Naturally Occurring Ehrlichia chaffeensis Infection in Coyotes from Oklahoma [PDF]
Emerging Infectious Diseases, 2000 A nested polymerase chain reaction assay was used to determine the presence of Ehrlichia chaffeensis, E. canis, and E. ewingii DNA in blood samples of free-ranging coyotes from central and north-central Oklahoma. Of the 21 coyotes examined, 15 (71%) were
Alan Kocan +5 more
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Proteomic analysis of the Ehrlichia chaffeensis phagosome in cultured DH82 cells. [PDF]
PLoS ONE, 2014 Ehrlichia chaffeensis is an obligately intracellular bacterium that resides and multiplies within cytoplasmic vacuoles of phagocytes. The Ehrlichia-containing vacuole (ECV) does not fuse with lysosomes, an essential condition for Ehrlichia to survive ...
Yan Cheng +8 more
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