Results 21 to 30 of about 9,885 (133)

Prolonged immune response to tick-borne Ehrlichia chaffeensis infection using a genetically modified live vaccine. [PDF]

Vaccine
Ehrlichia chaffeensis, a tick transmitted rickettsial bacterium, causes monocytic ehrlichiosis in humans and dogs. Earlier, we demonstrated that dogs immunized with a mutant strain of E. chaffeensis having a functional disruption in the gene encoding the
Madesh S, McGill J, Jaworski DC, Ferm J, Ferm D, Liu H, Fitzwater S, Nair A, Hove P, Alizadeh K, Knox C, Thackrah A, Ganta RR.   +12 more
europepmc   +2 more sources

Proteome analysis of Ehrlichia chaffeensis containing phagosome membranes revealed the presence of numerous bacterial and host proteins. [PDF]

Front Cell Infect Microbiol, 2022
Tick-transmitted Ehrlichia chaffeensis, the causative agent for human monocytic ehrlichiosis, resides and multiplies within a host cell phagosome. Infection progression of E.
Kondethimmanahalli C, Ganta RR.
europepmc   +2 more sources

Molecular detection of Ehrlichia chaffeensis in marsh deer (Blastocerus dichotomus) and their parasitic Amblyomma triste ticks in Argentina suggests a local transmission cycle. [PDF]

Parasit Vectors
Since the first finding of Ehrlichia chaffeensis in the Argentinian marsh deer populations in 2018, we have conducted ongoing surveillance efforts to better understand the ecological and epidemiological dynamics of this zoonotic tick-borne pathogen in ...
Guillemi EC, Orozco MM, Figini I, Blanco P, Farber MD.   +4 more
europepmc   +2 more sources

Ehrlichia chaffeensis Etf-3 Induces Host RAB15 Upregulation for Bacterial Intracellular Growth. [PDF]

Int J Mol Sci
Ehrlichia chaffeensis infects human monocytes or macrophages and causes human monocytic ehrlichiosis (HME), an emerging life-threatening zoonosis. After internalization, E. chaffeensis resides in membrane-bound inclusions, E.
Yang N, Li M, Qin S, Duan N, Li X, Zhou Y, Wang M, Jin Y, Wu W, Cheng Z.   +9 more
europepmc   +2 more sources

Genetic characterization of a novel Ehrlichia chaffeensis genotype from an Amblyomma tenellum tick from South Texas, USA. [PDF]

Ticks Tick Borne Dis, 2022
Ehrlichia chaffeensis is the causative agent of human monocytotropic ehrlichiosis (HME), a disease that ranges in severity from mild to fatal infection.
Arroyave E, Quade B, Mendell NL, Blanton LS, Bouyer DH.   +4 more
europepmc   +2 more sources

Host Cells Upregulate Phosphate Transporter PIT1 to Inhibit Ehrlichia chaffeensis Intracellular Growth. [PDF]

Int J Mol Sci
Ehrlichia chaffeensis infects and proliferates inside monocytes or macrophages and causes human monocytic ehrlichiosis (HME), an emerging life-threatening tick-borne zoonosis. After internalization, E.
Li M, Yang N, Li X, Duan N, Qin S, Wang M, Zhou Y, Jin Y, Wu W, Jin S, Cheng Z.   +10 more
europepmc   +2 more sources

Potential zoonotic role of the tick Amblyomma cf. oblongoguttatum (Ixodida: Ixodidae) in the bacterial transmission of Ehrlichia chaffeensis (Rickettsiales: Anaplasmataceae) in a deciduous tropical forest in Mexico. [PDF]

J Med Entomol
Ehrlichia chaffeensis is a bacterium belonging to the Anaplasmataceae family. In Mexico, only 2 species have been recorded in association with tick species and humans. The objective of the present study was to detect the presence of bacteria of the genus
Guzmán-Cornejo C, Herrera-Mares A, García-Prieto L, Oceguera-Figueroa A, López-Pérez AM, Dzul-Rosado K.   +5 more
europepmc   +2 more sources

Insights into the mechanism regulating the differential expression of the P28-OMP outer membrane proteins in obligatory intracellular pathogen Ehrlichia chaffeensis. [PDF]

Emerg Microbes Infect, 2021
Ehrlichia chaffeensis causes human monocytic ehrlichiosis (HME), which is one of the most prevalent, life-threatening emerging infectious zoonoses. The life cycle of E. chaffeensis includes ticks and mammals, in which E.
Duan N, Ma X, Cui H, Wang Z, Chai Z, Yan J, Li X, Feng Y, Cao Y, Jin Y, Bai F, Wu W, Rikihisa Y, Cheng Z.   +13 more
europepmc   +2 more sources

Detection of Rickettsia amblyommatis and Ehrlichia chaffeensis in Amblyomma americanum Inhabiting Two Urban Parks in Oklahoma. [PDF]

Vector Borne Zoonotic Dis, 2021
For the past 30 years, the number of people infected with causative agents of ehrlichiosis, Rocky Mountain spotted fever, and spotted fever group rickettiosis (SFGR) has increased in Oklahoma.
Small M, Brennan RE.
europepmc   +2 more sources

Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling. [PDF]

mSphere, 2021
Upon infecting mammalian hosts, Ehrlichia chaffeensis establishes a replicative niche in microbe-eating immune system cells where it expertly orchestrates infection and spread.
Rogan MR, Patterson LL, Byerly CD, Luo T, Paessler S, Veljkovic V, Quade B, McBride JW.   +7 more
europepmc   +2 more sources