Results 11 to 20 of about 9,793 (167)

Hacker Within! Ehrlichia chaffeensis Effector Driven Phagocyte Reprogramming Strategy [PDF]

Frontiers in Cellular and Infection Microbiology, 2016
Ehrlichia chaffeensis is a small, gram negative, obligately intracellular bacterium that preferentially infects mononuclear phagocytes. It is the etiologic agent of human monocytotropic ehrlichiosis (HME), an emerging life-threatening tick-borne zoonosis.
Taslima Taher Lina, Tierra eFarris, Tian eLuo, Shubhajit eMitra, Bing eZhu, Jere W McBride   +5 more
doaj   +5 more sources

Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling. [PDF]

mSphere, 2021
Upon infecting mammalian hosts, Ehrlichia chaffeensis establishes a replicative niche in microbe-eating immune system cells where it expertly orchestrates infection and spread.
Rogan MR, Patterson LL, Byerly CD, Luo T, Paessler S, Veljkovic V, Quade B, McBride JW.   +7 more
europepmc   +4 more sources

Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
Ehrlichia chaffeensis is an obligate intracellular bacterium that invades monocytes to cause the emerging and potentially severe disease, monocytic ehrlichiosis.
Ryan S. Green, Jerilyn R. Izac, Waheeda A. Naimi, Nathaniel O'Bier, Edward B. Breitschwerdt, Richard T. Marconi, Jason A. Carlyon   +6 more
doaj   +3 more sources

Molecular detection of Rickettsiales and a potential novel Ehrlichia species closely related to Ehrlichia chaffeensis in ticks (Acari: Ixodidae) from Shaanxi Province, China, in 2022 to 2023. [PDF]

Front Microbiol, 2023
Important tick-borne diseases include spotted fever group Rickettsia (SFGR), Anaplasma, and Ehrlichia, which cause harm to animal and human health. Ixodidae are the primary vectors of these pathogens.
Zhang X, Lv W, Teng Z, Zhao N, Zhou Y, Ma D, Ma L, Cheng Y, Wei J, He J, Ma W, Liu D, Qin T.   +12 more
europepmc   +2 more sources

Serological Evidence Supporting the Occurrence of Ehrlichia chaffeensis or a Closely Related Species in Brazilian Dogs. [PDF]

Pathogens, 2023
Ehrlichia chaffeensis is a tick-borne bacterium that causes human monocytotropic ehrlichiosis, an emerging life-threatening disease in humans transmitted by Amblyomma americanum. Although most studies have reported bacterial isolations and clinical cases
Taques IIGG, Melo ALT, Horta MC, Pereira NA, Aguiar DM.   +4 more
europepmc   +2 more sources

Inhibition of Ehrlichia chaffeensis infection by cell-permeable macrocyclic peptides that bind type IV secretion effector Etf-1. [PDF]

PNAS Nexus, 2023
Ehrlichia chaffeensis is an obligatory intracellular bacterium that infects monocytes and macrophages, and causes human monocytic ehrlichiosis, an emerging life-threatening infectious disease.
Lin M, Koley A, Zhang W, Pei D, Rikihisa Y.   +4 more
europepmc   +2 more sources

Multiple Ehrlichia chaffeensis genes critical for persistent infection in a vertebrate host are identified as nonessential for its growth in the tick vector; Amblyomma americanum. [PDF]

Front Cell Infect Microbiol, 2023
Ehrlichia chaffeensis is a tick-transmitted monocytic ehrlichiosis agent primarily causing the disease in people and dogs. We recently described the development and characterization of 55 random mutations in E.
Jaworski DC, Wang Y, Nair A, Liu H, Ganta RR.   +4 more
europepmc   +2 more sources

<i>Ehrlichia chaffeensis</i> proteomic profiling reveals distinct expression patterns of infectious and replicating forms. [PDF]

Front Cell Infect Microbiol
Ehrlichia chaffeensis is a tick-transmitted rickettsial pathogen responsible for causing human monocytic ehrlichiosis (HME). The pathogen’s developmental cycle includes infectious dense-core cells (DCs) and non-infectious replicating cells (RCs ...
Kondethimmanahalli C, Ganta RR.
europepmc   +2 more sources

Genome-Wide Subtraction Analysis and Reverse Vaccinology to Detect Novel Drug Targets and Potential Vaccine Candidates Against Ehrlichia chaffeensis. [PDF]

Appl Biochem Biotechnol, 2023
Human monocytotropic ehrlichiosis is an emerging tick-borne infection caused by the obligate intracellular pathogen, Ehrlichia chaffeensis . The non-specific symptoms can range from a self-limiting fever to a fatal septic-like syndrome and may be ...
Sabzi S, Shahbazi S, Noori Goodarzi N, Haririzadeh Jouriani F, Habibi M, Bolourchi N, Mirzaie A, Badmasti F.   +7 more
europepmc   +2 more sources

Proteome analysis of Ehrlichia chaffeensis containing phagosome membranes revealed the presence of numerous bacterial and host proteins. [PDF]

Front Cell Infect Microbiol, 2022
Tick-transmitted Ehrlichia chaffeensis, the causative agent for human monocytic ehrlichiosis, resides and multiplies within a host cell phagosome. Infection progression of E.
Kondethimmanahalli C, Ganta RR.
europepmc   +2 more sources