Results 11 to 20 of about 9,885 (133)

Serological Evidence Supporting the Occurrence of Ehrlichia chaffeensis or a Closely Related Species in Brazilian Dogs. [PDF]

Pathogens, 2023
Ehrlichia chaffeensis is a tick-borne bacterium that causes human monocytotropic ehrlichiosis, an emerging life-threatening disease in humans transmitted by Amblyomma americanum. Although most studies have reported bacterial isolations and clinical cases
Taques IIGG, Melo ALT, Horta MC, Pereira NA, Aguiar DM.   +4 more
europepmc   +2 more sources

Ehrlichia chaffeensis DNA in Haemaphysalis longicornis Ticks, Connecticut, USA. [PDF]

Emerg Infect Dis
Informed by passive tick surveillance, we collected questing Haemaphysalis longicornis ticks from southwestern Connecticut, USA. Of 445 ticks tested by PCR, 3 nymphs were positive: 1 for Ehrlichia chaffeensis and 2 for Borrelia burgdorferi.
Molaei G, Mohapatra AR, Khalil N, Cozens D, Bonilla D.   +4 more
europepmc   +2 more sources

Inhibition of Ehrlichia chaffeensis infection by cell-permeable macrocyclic peptides that bind type IV secretion effector Etf-1. [PDF]

PNAS Nexus, 2023
Ehrlichia chaffeensis is an obligatory intracellular bacterium that infects monocytes and macrophages, and causes human monocytic ehrlichiosis, an emerging life-threatening infectious disease.
Lin M, Koley A, Zhang W, Pei D, Rikihisa Y.   +4 more
europepmc   +2 more sources

Donor-Derived Ehrlichiosis Caused by Ehrlichia chaffeensis from Living Donor Kidney Transplant. [PDF]

Emerg Infect Dis
Tickborne infections are challenging to diagnose, particularly among solid organ transplant recipients. We report a US case of donor-derived ehrlichiosis from a living kidney donation that highlights how screening for living donors may miss tickborne ...
Scolarici MJ, Kuehler D, Osborn R, Doyle A, Schiffman EK, Garvin A, Villalba JA, Ramos CJ, Paddock CD, Annambhotla PD, Taylor M, Salzer JS, Saddler C, Thiessen C, Kandaswamy R, Odorico J.   +15 more
europepmc   +2 more sources

<i>Ehrlichia chaffeensis</i> proteomic profiling reveals distinct expression patterns of infectious and replicating forms. [PDF]

Front Cell Infect Microbiol
Ehrlichia chaffeensis is a tick-transmitted rickettsial pathogen responsible for causing human monocytic ehrlichiosis (HME). The pathogen’s developmental cycle includes infectious dense-core cells (DCs) and non-infectious replicating cells (RCs ...
Kondethimmanahalli C, Ganta RR.
europepmc   +2 more sources

Multiple Ehrlichia chaffeensis genes critical for persistent infection in a vertebrate host are identified as nonessential for its growth in the tick vector; Amblyomma americanum. [PDF]

Front Cell Infect Microbiol, 2023
Ehrlichia chaffeensis is a tick-transmitted monocytic ehrlichiosis agent primarily causing the disease in people and dogs. We recently described the development and characterization of 55 random mutations in E.
Jaworski DC, Wang Y, Nair A, Liu H, Ganta RR.   +4 more
europepmc   +2 more sources

Serosurvey of <i>Anaplasma phagocytophilum</i>, <i>Babesia microti</i>, and <i>Ehrlichia chaffeensis</i> in Quilombola Communities of Southern Brazil. [PDF]

Pathogens
Although quilombola individuals and their dogs may be exposed to hemoparasites such as A. phagocytophilum, B. microti, and E. chaffeensis, no study to date has been conducted in these populations.
França DA, Kmetiuk LB, Silva FPD, Panazzolo GK, Biondo LM, Domingues OJ, Fávero GM, Duré AÍL, Biondo AW.   +8 more
europepmc   +2 more sources

Evaluating EcxR for Its Possible Role in Ehrlichia chaffeensis Gene Regulation. [PDF]

Int J Mol Sci, 2022
Ehrlichia chaffeensis, a tick-transmitted intraphagosomal bacterium, is the causative agent of human monocytic ehrlichiosis. The pathogen also infects several other vertebrate hosts. E.
Liu H, Knox CA, Jakkula LUMR, Wang Y, Peddireddi L, Ganta RR.   +5 more
europepmc   +2 more sources

Genome-Wide Subtraction Analysis and Reverse Vaccinology to Detect Novel Drug Targets and Potential Vaccine Candidates Against Ehrlichia chaffeensis. [PDF]

Appl Biochem Biotechnol, 2023
Human monocytotropic ehrlichiosis is an emerging tick-borne infection caused by the obligate intracellular pathogen, Ehrlichia chaffeensis . The non-specific symptoms can range from a self-limiting fever to a fatal septic-like syndrome and may be ...
Sabzi S, Shahbazi S, Noori Goodarzi N, Haririzadeh Jouriani F, Habibi M, Bolourchi N, Mirzaie A, Badmasti F.   +7 more
europepmc   +2 more sources

Long-Term Protective Immunity against Ehrlichia chaffeensis Infection Induced by a Genetically Modified Live Vaccine. [PDF]

Vaccines (Basel)
Human monocytic ehrlichiosis, an emerging tick-borne disease, is caused by Ehrlichia chaffeensis. Infections with the pathogen are also common in the canine host. Our previous studies demonstrated that functional disruption within the E.
Madesh S, McGill J, Jaworski DC, Ferm J, Liu H, Fitzwater S, Hove P, Ferm D, Nair A, Knox CA, Alizadeh K, Thackrah A, Ganta RR.   +12 more
europepmc   +2 more sources