Results 1 to 10 of about 9,885 (133)

Antibody reactive immunomes of Ehrlichia chaffeensis and E. canis are diverse and defined by conformational antigenic determinants. [PDF]

Front Cell Infect Microbiol, 2023
For decades, the defined antibody reactive proteins of Ehrlichia chaffeensis and E. canis were limited to a small group with linear antibody epitopes.
Luo T, Patel JG, Zhang X, McBride JW.
europepmc   +4 more sources

Ehrlichia chaffeensis Co-Opts Phagocytic Hemocytes for Systemic Dissemination in the Lone Star Tick, Amblyomma americanum. [PDF]

J Innate Immun, 2023
Introduction: Hematophagous arthropods can acquire and transmit several pathogens of medical importance. In ticks, the innate immune system is crucial in the outcome between vector-pathogen interaction and overall vector competence. However, the specific
Adegoke A, Hanson J, Smith RC, Karim S.
europepmc   +4 more sources

Efficacy and Immune Correlates of OMP-1B and VirB2-4 Vaccines for Protection of Dogs from Tick Transmission of Ehrlichia chaffeensis. [PDF]

mBio, 2022
Ehrlichia are tick-borne pathogens that cause a potentially fatal illness—ehrlichiosis—in animals and humans worldwide. Currently, no vaccine is available for ehrlichiosis, and treatment options are limited.
Budachetri K, Lin M, Chien RC, Zhang W, Brock GN, Rikihisa Y.   +5 more
europepmc   +4 more sources

The "Biological Weapons" of Ehrlichia chaffeensis: Novel Molecules and Mechanisms to Subjugate Host Cells. [PDF]

Front Cell Infect Microbiol, 2021
Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic ehrlichiosis, an emerging, potentially fatal tick-borne infectious disease.
Rikihisa Y.
europepmc   +4 more sources

Glutathione Synthesis Regulated by CtrA Protects Ehrlichia chaffeensis From Host Cell Oxidative Stress. [PDF]

Front Microbiol, 2022
Ehrlichia chaffeensis, a small Gram-negative obligatory intracellular bacterium, infects human monocytes or macrophages, and causes human monocytic ehrlichiosis, one of the most prevalent, life-threatening emerging zoonoses.
Yan J, Liang Q, Chai Z, Duan N, Li X, Liu Y, Yang N, Li M, Jin Y, Bai F, Wu W, Cheng Z.   +11 more
europepmc   +4 more sources

Transmission of Ehrlichia chaffeensis From an Organ Donor to a Kidney-Pancreas Transplant Recipient. [PDF]

Transpl Infect Dis
Transplant Infectious Disease, Volume 27, Issue 5, September/October 2025.
Gundelly P, Ransom E, Stewart Z, Ruch B, Jittirat A, Denny L, Kasten J, Taylor ML, Salzer JS, Basavaraju SV, Annambhotla P, McCormick DW, Gleaton AN, Karpathy SE, Singleton J, Ramos C, Paddock CD, Rothfeldt LK, Baker M, Villalba JA.   +19 more
europepmc   +3 more sources

Ehrlichia chaffeensis TRP120 ubiquitinates tumor suppressor APC to modulate Hippo and Wnt signaling. [PDF]

Front Cell Dev Biol
Ehrlichia chaffeensis: TRP120 is a multifunctional effector that acts as a ligand mimic to activate evolutionary conserved eukaryotic signaling pathways Notch, Wnt, Hedgehog and Hippo.
Byerly CD, Zhu B, Warwick PA, Patterson LL, Pittner NA, McBride JW.   +5 more
europepmc   +4 more sources

CtrA activates the expression of glutathione S-transferase conferring oxidative stress resistance to Ehrlichia chaffeensis. [PDF]

Front Cell Infect Microbiol, 2022
Ehrlichia chaffeensis, the causative agent of human monocytic ehrlichiosis (HME), is a Gram-negative obligatory intracellular bacterium, which infects and multiplies in human monocytes and macrophages.
Liang Q, Yan J, Zhang S, Yang N, Li M, Jin Y, Bai F, Wu W, Cheng Z.   +8 more
europepmc   +4 more sources

Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation. [PDF]

mBio, 2020
Ehrlichia chaffeensis is an obligatory intracellular bacterium with the capability of causing an emerging infectious disease called human monocytic ehrlichiosis. E.
Teymournejad O, Rikihisa Y.
europepmc   +4 more sources

Molecular detection of Rickettsiales and a potential novel Ehrlichia species closely related to Ehrlichia chaffeensis in ticks (Acari: Ixodidae) from Shaanxi Province, China, in 2022 to 2023. [PDF]

Front Microbiol, 2023
Important tick-borne diseases include spotted fever group Rickettsia (SFGR), Anaplasma, and Ehrlichia, which cause harm to animal and human health. Ixodidae are the primary vectors of these pathogens.
Zhang X, Lv W, Teng Z, Zhao N, Zhou Y, Ma D, Ma L, Cheng Y, Wei J, He J, Ma W, Liu D, Qin T.   +12 more
europepmc   +2 more sources