Results 1 to 10 of about 336,233 (114)

Nanomedicines for the Efficient Treatment of Intracellular Bacteria: The “ART” Principle [PDF]

Frontiers in Chemistry, 2021
Infections induced by bacteria at present are a severe threat to public health. Compared with extracellular bacteria, intracellular bacteria are harder to get rid of and readily induce chronic inflammation as well as autoimmune disorders.
Hongzhao Qi, Peipei Shan, Yin Wang, Peifeng Li, Kun Wang, Lijun Yang   +5 more
doaj   +4 more sources

CTLs: Killers of intracellular bacteria [PDF]

Frontiers in Cellular and Infection Microbiology, 2022
Many microbial pathogens have evolved a range of capabilities to evade host immune defense mechanisms and to survive and multiply in host cells. The presence of host intracellular bacteria makes it difficult for specific antibodies to function. After the
Li Tian, Wei Zhou, Xianwei Wu, Zhuannan Hu, Lei Qiu, Huiyong Zhang, Xue Chen, Shaoyan Zhang, Zhenhui Lu   +8 more
doaj   +2 more sources

Intracellular bacteria in cancer—prospects and debates [PDF]

npj Biofilms and Microbiomes, 2023
Recent evidence suggests that some human cancers may harbor low-biomass microbial ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in this context, are suggested by these studies to localize within cancer cells ...
Lena Schorr, Marius Mathies, Eran Elinav, Jens Puschhof   +3 more
doaj   +2 more sources

Vaccine development: obligate intracellular bacteria new tools, old pathogens: the current state of vaccines against obligate intracellular bacteria [PDF]

Frontiers in Cellular and Infection Microbiology
Obligate intracellular bacteria have remained those for which effective vaccines are unavailable, mostly because protection does not solely rely on an antibody response.
E. J. van Schaik, A. P. Fratzke, A. P. Fratzke, A. E. Gregory, A. E. Gregory, Jennifer E. Dumaine, J. E. Samuel, J. E. Samuel   +7 more
doaj   +2 more sources

Antibiotic-loaded lactoferrin nanoparticles as a platform for enhanced infection therapy through targeted elimination of intracellular bacteria [PDF]

Asian Journal of Pharmaceutical Sciences
Intracellular bacteria can multiply inside host cells and manipulate their biology, and the efficacy of traditional antibiotic drug therapy for intracellular bacteria is limited by inadequate drug accumulation.
Wei Wang, Wanying Mo, Xue Xiao, Manying Cai, Songfu Feng, Yupeng Wang, Dongfang Zhou   +6 more
doaj   +2 more sources

Eukaryotic Cell Permeabilisation to Identify New Putative Chlamydial Type III Secretion System Effectors Secreted within Host Cell Cytoplasm

Microorganisms, 2020
Chlamydia trachomatis and Waddlia chondrophila are strict intracellular bacteria belonging to the Chlamydiales order. C. trachomatis is the most frequent bacterial cause of genital and ocular infections whereas W.
Carole Kebbi-Beghdadi, Ludovic Pilloux, Virginie Martin, Gilbert Greub   +3 more
doaj   +1 more source

Diverse Stress-Inducing Treatments cause Distinct Aberrant Body Morphologies in the Chlamydia-Related Bacterium, Waddlia chondrophila

Microorganisms, 2020
Chlamydiae, such as Chlamydia trachomatis and Chlamydia pneumoniae, can cause chronic infections. It is believed that persistent forms called aberrant bodies (ABs) might be involved in this process.
Aurélie Scherler, Nicolas Jacquier, Carole Kebbi-Beghdadi, Gilbert Greub   +3 more
doaj   +1 more source

Presence and diversity of Chlamydiae bacteria in Spinturnix myoti, an ectoparasite of bats

Parasite, 2020
Chlamydia spp. and Chlamydia-like organisms are able to infect vertebrates such as mammals, reptiles and birds, but also arthropods and protozoans. Since they have been detected in bats and bat feces, we expected Chlamydiae bacteria to also be present in
Thiévent Kevin, Szentiványi Tamara, Aeby Sébastien, Glaizot Olivier, Christe Philippe, Greub Gilbert   +5 more
doaj   +1 more source

Intracellular Bacterial Symbionts in Corals: Challenges and Future Directions

Microorganisms, 2021
Corals are the main primary producers of coral reefs and build the three-dimensional reef structure that provides habitat to more than 25% of all marine eukaryotes.
Justin Maire, Linda L. Blackall, Madeleine J. H. van Oppen   +2 more
doaj   +1 more source

Engineering Cyborg Bacteria Through Intracellular Hydrogelation

Advanced Science, 2023
Natural and artificial cells are two common chassis in synthetic biology. Natural cells can perform complex tasks through synthetic genetic constructs, but their autonomous replication often causes safety concerns for biomedical applications. In contrast,
Luis E. Contreras‐Llano, Yu‐Han Liu, Tanner Henson, Conary C. Meyer, Ofelya Baghdasaryan, Shahid Khan, Chi‐Long Lin, Aijun Wang, Che‐Ming J. Hu, Cheemeng Tan   +9 more
doaj   +1 more source