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Immunity to intracellular bacteria [PDF]
Immunity to intracellular bacteria including Mycobacterium tuberculosis. Mycobacterium leprae, and Listeria monocytogenes depends on specific T cells. Evidence to be described suggests that CD4 (alpha/beta)T cells which interact with each other and with ...
Stefan H. E. Kaufmann +2 more
doaj +7 more sources
Challenges in Drug Discovery for Intracellular Bacteria [PDF]
Novel drugs are needed to treat a variety of persistent diseases caused by intracellular bacterial pathogens. Virulence pathways enable many functions required for the survival of these pathogens, including invasion, nutrient acquisition, and immune ...
Allison N. Tucker +2 more
doaj +3 more sources
Intracellular biomineralization in bacteria [PDF]
Bacteria can sequester metals and other ions intracellularly in various forms ranging from poorly ordered deposits to well- ordered mineral crystals. Magnetotactic bacteria provide one example of such intracellular deposits. They synthesize intracellular magnetic minerals of magnetite (Fe3O4) and/or greigite (Fe3S4) magnetosomes which are generally ...
Wei eLin +5 more
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Peptidoglycan in obligate intracellular bacteria [PDF]
SummaryPeptidoglycan is the predominant stress‐bearing structure in the cell envelope of most bacteria, and also a potent stimulator of the eukaryotic immune system. Obligate intracellular bacteria replicate exclusively within the interior of living cells, an osmotically protected niche. Under these conditions peptidoglycan is not necessarily needed to
Christian Otten +4 more
openaire +7 more sources
Pyroptosis in defense against intracellular bacteria. [PDF]
Pathogenic microbes invade the human body and trigger a host immune response to defend against the infection. In response, host-adapted pathogens employ numerous virulence strategies to overcome host defense mechanisms. As a result, the interaction between the host and pathogen is a dynamic process that shapes the evolution of the host's immune ...
Li L, Dickinson MS, Coers J, Miao EA.
europepmc +3 more sources
Carbon metabolism of intracellular bacteria [PDF]
Bacterial metabolism has been studied intensively since the first observations of these 'animalcules' by Leeuwenhoek and their isolation in pure cultures by Pasteur. Metabolic studies have traditionally focused on a small number of model organisms, primarily the Gram negative bacillus Escherichia coli, adapted to artificial culture conditions in the ...
Ernesto J, Muñoz-Elías +1 more
openaire +2 more sources
Roles of bovine Waddlia chondrophila and Chlamydia trachomatis in human preterm birth
Waddlia chondrophila and Chlamydia trachomatis are intracellular bacteria associated with human miscarriage. We investigated their role in human preterm birth.
D. Baud +6 more
doaj +1 more source
Intracellular bacteria encode inhibitory SNARE-like proteins. [PDF]
Pathogens use diverse molecular machines to penetrate host cells and manipulate intracellular vesicular trafficking. Viruses employ glycoproteins, functionally and structurally similar to the SNARE proteins, to induce eukaryotic membrane fusion ...
Fabienne Paumet +7 more
doaj +1 more source
Waddlia chondrophila, an obligate intracellular bacterium of the Chlamydiales order, is considered as an agent of bovine abortion and a likely cause of miscarriage in humans.
J. Lienard +6 more
doaj +1 more source
What is the true clinical relevance of Simkania negevensis and other emerging Chlamydiales members?
Waddlia chondrophila and Simkania negevensis are emerging Chlamydia-related bacteria. Similar to the pathogenic organisms Chlamydia pneumoniae and Chlamydia trachomatis, these emerging bacteria are implicated in human genital infections and respiratory ...
M. Vouga +5 more
doaj +1 more source

