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Functional genomics of intracellular bacteria [PDF]
During the genomic era, a large amount of whole-genome sequences accumulated, which identified many hypothetical proteins of unknown function. Rapidly, functional genomics, which is the research domain that assign a function to a given gene product, has thus been developed.
de Barsy, Marie, Greub, Gilbert
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A growing number of human infections incriminate environmental bacteria that have evolved virulent mechanisms to resist amoebae and use them as a replicative niche. These bacteria are designated amoeba-resisting bacteria (ARB).
J. Lienard +6 more
doaj +1 more source
Absence of Chlamydia-like organisms in pigs
Porcine reproductive failure, especially abortion, causes significant economic loss in the pig industry. Waddlia chondrophila and Parachlamydia acanthamoebae are potential abortigenic agents for pigs.
M. Van Gils +3 more
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Pathogenic mechanisms of intracellular bacteria [PDF]
Purpose of review We wished to overview recent data on a subset of epigenetic changes elicited by intracellular bacteria in human cells. Reprogramming the gene expression pattern of various host cells may facilitate bacterial growth, survival, and spread.
Niller Hans Helmut +4 more
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Introduction: Miscarriage is one of the most common adverse pregnancy outcomes. The aim of this study was to investigate the relationship between miscarriage in humans and infections caused by zoonotic bacteria and genital pathogens.
Mariem Smaoui +13 more
doaj +1 more source
Lipid Droplets: A Significant but Understudied Contributor of Host–Bacterial Interactions
Lipid droplets (LDs) are cytosolic lipid storage organelles that are important for cellular lipid metabolism, energy homeostasis, cell signaling, and inflammation.
Cassandra L. Libbing +4 more
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Lawsonia intracellularis is an obligate intracellular bacterium and causative agent of proliferative enteropathy. The pathogenesis of L. intracellularis is not completely understood, including the endocytic mechanisms to access the host cell cytoplasm ...
Carlos Eduardo Real Pereira +7 more
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Antimicrobial Peptides and Cell-Penetrating Peptides for Treating Intracellular Bacterial Infections
Bacterial infections caused by intracellular pathogens are difficult to control. Conventional antibiotic therapies are often ineffective, as high doses are needed to increase the number of antibiotics that will cross the host cell membrane to act on the ...
Danieli F. Buccini +4 more
doaj +1 more source
Identification of αB-Crystallin, a Biomarker of Renal Cell Carcinoma by SELDI-TOF MS
Spectrometric-based surface-enhanced laser desorption/ionization ProteinChip (SELDI-TOF) facilitates rapid and easy analysis of protein mixtures and is often exploited to define potential diagnostic markers from sera.
J. Holcakova +7 more
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Urinary tract infections (UTIs) affect a major proportion of the world population but have limited non-antibiotic-based therapeutic and preventative strategies against UTIs. Facultative intracellular uropathogens such as strains of uropathogenic E. coli,
Prema S. Prakash +4 more
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