Results 31 to 40 of about 3,995 (206)

Ehrlichia chaffeensis:a Prototypical Emerging Pathogen [PDF]

Clinical Microbiology Reviews, 2003
SUMMARYEhrlichia chaffeensis is an obligately intracellular, tick-transmitted bacterium that is maintained in nature in a cycle involving at least one and perhaps several vertebrate reservoir hosts. The moderate to severe disease caused by E. chaffeensis in humans, first identified in 1986 and reported for more than 1,000 patients through 2000 ...
Paddock, Christopher D, Childs, James E.
openaire   +3 more sources

The developmental cycle of Ehrlichia chaffeensis in vertebrate cells [PDF]

Cellular Microbiology, 2007
Ehrlichia chaffeensis, an obligatory intracellular bacterium, has two forms in mammalian cells: small dense-cored cells (DC) with dense nucleoid and larger reticulate cells (RC) with uniformly dispersed nucleoid. We have determined by electron microscopy that DC but not RC attaches to and enters into the host cells and RC but not DC multiples inside ...
Jian-zhi, Zhang, Vsevolod L, Popov, Si, Gao, David H, Walker, Xue-jie, Yu   +4 more
openaire   +2 more sources

Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation

mBio, 2020
The obligatory intracellular pathogen Ehrlichia chaffeensis lacks most factors that could respond to oxidative stress (a host cell defense mechanism).
Omid Teymournejad, Yasuko Rikihisa
doaj   +1 more source

Ehrlichia chaffeensis infection in the reservoir host (white-tailed deer) and in an incidental host (dog) is impacted by its prior growth in macrophage and tick cell environments. [PDF]

PLoS ONE, 2014
Ehrlichia chaffeensis, transmitted from Amblyomma americanum ticks, causes human monocytic ehrlichiosis. It also infects white-tailed deer, dogs and several other vertebrates. Deer are its reservoir hosts, while humans and dogs are incidental hosts.
Arathy D S Nair, Chuanmin Cheng, Deborah C Jaworski, Lloyd H Willard, Michael W Sanderson, Roman R Ganta   +5 more
doaj   +1 more source

Surface-Exposed Proteins ofEhrlichia chaffeensis [PDF]

Infection and Immunity, 2007
ABSTRACTThe surface proteins ofEhrlichia chaffeensisprovide an important interface for pathogen-host interactions. To investigate the surface proteins ofE. chaffeensis, membrane-impermeable, cleavable Sulfo-NHS-SS-Biotin was used to label intact bacteria.
Yan, Ge, Yasuko, Rikihisa
openaire   +2 more sources

Experimental infection of dairy calves with Ehrlichia chaffeensis [PDF]

Journal of Medical Microbiology, 2007
Human monocytic ehrlichiosis (HME) is a zoonotic emerging tick-borne disease with clinical signs that range from mild symptoms to multiple organ failure and death.Ehrlichia chaffeensis, the aetiologic agent of HME, is reported to infect a divergent range of mammals.
Jose R C, Delos Santos, Kirsten, Boughan, William G, Bremer, Brian, Rizzo, John J, Schaefer, Yasuko, Rikihisa, Glen R, Needham, L A, Capitini, David E, Anderson, Michael, Oglesbee, S A, Ewing, Roger W, Stich   +11 more
openaire   +2 more sources

Modeling the effects of Ehrlichia Chaffeensis and movement on dogs

Complexity, 2023
Abstract Ehrlichia chaffeensis is a tick-borne infectious disease transmitted by amblyomma americanum tick. This infectious disease was discovered in the 1970s when military dogs were returning from the Vietnam war.
Folashade B. Agusto, Jaimie Drum
openaire   +2 more sources

DETECTION OF ANTIBODIES REACTIVE WITH EHRLICHIA CHAFFEENSIS IN THE RACCOON [PDF]

Journal of Wildlife Diseases, 2000
Antibodies reactive with Ehrlichia chaffeensis were detected in raccoon (Procyon lotor) serum samples by using an indirect immunofluorescence assay. Samples from 411 raccoons trapped in the southeastern United States from 1977 to 1999 were tested. Serologically reactive samples with reciprocal titers of > or =16 were detected from 83 raccoons (20 ...
J A, Comer, W L, Nicholson, C D, Paddock, J W, Sumner, J E, Childs   +4 more
openaire   +2 more sources

Tick-borne ehrlichiosis infection in human beings [PDF]

Journal of Vector Borne Diseases, 2008
Human monocytic ehrlichiosis is a tick-borne infectious disease transmitted by several tick species, especially Amblyomma spp caused by Ehrlichia chaffeensis. E. chaffeensis is an obligatory intracellular, tick-transmitted bacterium that is maintained in
S. Ganguly, S.K. Mukhopadhayay
doaj  

EtpE Binding to DNase X Induces Ehrlichial Entry via CD147 and hnRNP-K Recruitment, Followed by Mobilization of N-WASP and Actin

mBio, 2015
Obligate intracellular bacteria, such as Ehrlichia chaffeensis, perish unless they can enter eukaryotic cells. E. chaffeensis is the etiological agent of human monocytic ehrlichiosis, an emerging infectious disease.
Dipu Mohan Kumar, Mingqun Lin, Qingming Xiong, Mathew James Webber, Comert Kural, Yasuko Rikihisa   +5 more
doaj   +1 more source