Results 31 to 40 of about 9,885 (133)

Mutations in Ehrlichia chaffeensis Genes ECH_0660 and ECH_0665 Cause Transcriptional Changes in Response to Zinc or Iron Limitation. [PDF]

J Bacteriol, 2021
Ehrlichia chaffeensis, a tick-transmitted bacterium, causes human monocytic ehrlichiosis by replicating within phagosomes of monocytes/macrophages. A function disruption mutation within the pathogen’s gene encoding a phage head-to-tail connector protein ...
Torres-Escobar A, Juárez-Rodríguez MD, Ganta RR.   +2 more
europepmc   +2 more sources

Immunoreactive Protein Repertoires of Ehrlichia chaffeensis and E. canis Reveal the Dominance of Hypothetical Proteins and Conformation-Dependent Antibody Epitopes. [PDF]

Infect Immun, 2021
The immunomes of Ehrlichia chaffeensis and Ehrlichia canis have recently been revised to include immunodominant hypothetical proteins with conformational antibody epitopes. In this study, we examined 216 E. chaffeensis and 190 E.
Luo T, Patel JG, Zhang X, Walker DH, McBride JW.   +4 more
europepmc   +2 more sources

Analysis of <i>Amblyomma americanum</i> microRNAs in response to <i>Ehrlichia chaff</i>eensis infection and their potential role in vectorial capacity. [PDF]

Front Cell Infect Microbiol
Background MicroRNAs (miRNAs) represent a subset of small noncoding RNAs and carry tremendous potential for regulating gene expression at the post-transcriptional level.
Kumar D, Budachetri K, Rikihisa Y, Karim S.   +3 more
europepmc   +2 more sources

Functional Characterization of Multiple Ehrlichia chaffeensis Sodium (Cation)/Proton Antiporter Genes Involved in the Bacterial pH Homeostasis. [PDF]

Int J Mol Sci, 2021
Ehrlichia chaffeensis causes human monocytic ehrlichiosis. Little is known about how this and other related tick-borne rickettsia pathogens maintain pH homeostasis in acidified phagosomes and the extracellular milieu.
Wei L, Liu H, Alizadeh K, Juarez-Rodriguez MD, Ganta RR.   +4 more
europepmc   +2 more sources

Alpha Enolase 1 Ubiquitination and Degradation Mediated by Ehrlichia chaffeensis TRP120 Disrupts Glycolytic Flux and Promotes Infection. [PDF]

Pathogens, 2021
Ehrlichia chaffeensis modulates numerous host cell processes, including gene transcription to promote infection of the mononuclear phagocyte. Modulation of these host cell processes is directed through E. chaffeensis effectors, including TRP120.
Zhu B, McBride JW.
europepmc   +2 more sources

Ehrlichia chaffeensis and Four Anaplasma Species With Veterinary and Public Health Significance Identified in Tibetan Sheep (Ovis aries) and Yaks (Bos grunniens) in Qinghai, China. [PDF]

Front Vet Sci, 2021
Tick-borne diseases (TBDs) can cause serious economic losses and are very important to animal and public health. To date, research on TBDs has been limited in Qinghai-Tibet Plateau, China.
Wang Y, Zhang Q, Han S, Li Y, Wang B, Yuan G, Zhang P, Yang Z, Zhang H, Sun Y, Chen J, Han X, He H.   +12 more
europepmc   +2 more sources

Protein and DNA Biosynthesis Demonstrated in Host Cell-Free Phagosomes Containing Anaplasma phagocytophilum or Ehrlichia chaffeensis in Axenic Media. [PDF]

Infect Immun, 2021
Rickettsiae belong to the Anaplasmataceae family, which includes mostly tick-transmitted pathogens causing human, canine, and ruminant diseases. Biochemical characterization of the pathogens remains a major challenge because of their obligate parasitism.
Zhang Y, Chen L, Kondethimmanahalli C, Liu H, Ganta RR.   +4 more
europepmc   +2 more sources

Host membrane lipids are trafficked to membranes of intravacuolar bacterium Ehrlichia chaffeensis. [PDF]

Proc Natl Acad Sci U S A, 2020
Significance Biological membranes are essential for life. Although bacteria and eukaryotic cells have evolved to produce membranes of different compositions, several bacterial pathogens can hijack and utilize host-synthesized membrane lipids.
Lin M, Grandinetti G, Hartnell LM, Bliss D, Subramaniam S, Rikihisa Y.   +5 more
europepmc   +2 more sources

Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection. [PDF]

Front Cell Infect Microbiol, 2020
Ehrlichia chaffeensis is an obligate intracellular bacterium that invades monocytes to cause the emerging and potentially severe disease, monocytic ehrlichiosis.
Green RS, Izac JR, Naimi WA, O'Bier N, Breitschwerdt EB, Marconi RT, Carlyon JA.   +6 more
europepmc   +2 more sources

Evidence of Ehrlichia chaffeensis in Argentina through molecular detection in marsh deer (Blastocerus dichotomus). [PDF]

Int J Parasitol Parasites Wildl, 2019
Vector-borne pathogens are responsible for serious emerging diseases and have been widely described in wildlife. Ehrlichia chaffeensis causes the zoonotic “monocytic ehrlichiosis” in humans, is transmitted by the tick Amblyomma americanum and its ...
Guillemi EC, Orozco MM, Argibay HD, Farber MD.   +3 more
europepmc   +2 more sources