Ehrlichia chaffeensis:a Prototypical Emerging Pathogen [PDF]
Clinical Microbiology Reviews, 2003 SUMMARYEhrlichia chaffeensis is an obligately intracellular, tick-transmitted bacterium that is maintained in nature in a cycle involving at least one and perhaps several vertebrate reservoir hosts. The moderate to severe disease caused by E. chaffeensis in humans, first identified in 1986 and reported for more than 1,000 patients through 2000 ...
Paddock, Christopher D, Childs, James E.
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Surface-Exposed Proteins ofEhrlichia chaffeensis [PDF]
Infection and Immunity, 2007 ABSTRACTThe surface proteins ofEhrlichia chaffeensisprovide an important interface for pathogen-host interactions. To investigate the surface proteins ofE. chaffeensis, membrane-impermeable, cleavable Sulfo-NHS-SS-Biotin was used to label intact bacteria.
Yasuko Rikihisa, Yan Ge
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DETECTION OF ANTIBODIES REACTIVE WITH EHRLICHIA CHAFFEENSIS IN THE RACCOON [PDF]
Journal of Wildlife Diseases, 2000 Antibodies reactive with Ehrlichia chaffeensis were detected in raccoon (Procyon lotor) serum samples by using an indirect immunofluorescence assay. Samples from 411 raccoons trapped in the southeastern United States from 1977 to 1999 were tested. Serologically reactive samples with reciprocal titers of > or =16 were detected from 83 raccoons (20 ...
John W. Sumner +4 more
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The developmental cycle of Ehrlichia chaffeensis in vertebrate cells [PDF]
Cellular Microbiology, 2007 Ehrlichia chaffeensis, an obligatory intracellular bacterium, has two forms in mammalian cells: small dense-cored cells (DC) with dense nucleoid and larger reticulate cells (RC) with uniformly dispersed nucleoid. We have determined by electron microscopy that DC but not RC attaches to and enters into the host cells and RC but not DC multiples inside ...
David H. Walker +4 more
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Development of a polyclonal competitive enzyme-linked immunosorbent assay for detection of antibodies to Ehrlichia ruminantium [PDF]
, 2003 A polyclonal competitive enzyme-linked immunosorbent assay (PC-ELISA) is described for detection of antibodies to Ehrlichia (Cowdria) ruminantium by using a soluble extract of endothelial cell culture-derived E.
Bell-Sakyi, Lesley +2 more
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Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics. [PDF]
, 2020 As sequencing read length has increased, researchers have quickly adopted longer reads for their experiments. Here, we examine 14 pathogen or host-pathogen differential gene expression data sets to assess whether using longer reads is warranted.
Bruno, Vincent M +9 more
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Experimental infection of dairy calves with Ehrlichia chaffeensis [PDF]
Journal of Medical Microbiology, 2007 Human monocytic ehrlichiosis (HME) is a zoonotic emerging tick-borne disease with clinical signs that range from mild symptoms to multiple organ failure and death.Ehrlichia chaffeensis, the aetiologic agent of HME, is reported to infect a divergent range of mammals.
Kirsten Boughan +11 more
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Differentiation of stable kidney function versus progressive dysfunction in dogs
Journal of Veterinary Internal Medicine, Volume 37, Issue 6, Page 2241-2250, November/December 2023., 2023 Abstract Background Circulating creatinine and symmetric dimethylarginine (SDMA) are biomarkers of kidney function that have been used variously to define stable vs progressive chronic kidney disease (CKD). Slope monitoring of inverse biomarker values (creatinine−1 or SDMA−1) has shown promise, but quantitative criteria to distinguish stable vs ...
Larry D. Cowgill +13 more
wiley +1 more source
New species of Ehrlichia isolated from Rhipicephalus (Boophilus) microplus shows an ortholog of the E. canis major immunogenic glycoprotein gp36 with a new sequence of tandem repeats [PDF]
, 2017 This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.[Background]: Ehrlichia species are the etiological agents of emerging and life-threatening tick-borne human zoonoses that inflict serious and
Cabezas-Cruz, Alejandro +4 more
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Experimental infection of Rhipicephalus sanguineus with Ehrlichia chaffeensis [PDF]
Veterinary Microbiology, 2014 Ehrlichia chaffeensis, the etiologic agent of human monocytic ehrlichiosis, is a tick-borne rickettsial pathogen that is infective to a wide range of mammals, including dogs and people. Amblyomma americanum, the lone star tick, is considered the primary vector of E.
Ryan T. Stoffel +10 more
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