Results 61 to 70 of about 12,263 (237)

Ehrlichia chaffeensis:a Prototypical Emerging Pathogen [PDF]

Clinical Microbiology Reviews, 2003
SUMMARYEhrlichia chaffeensis is an obligately intracellular, tick-transmitted bacterium that is maintained in nature in a cycle involving at least one and perhaps several vertebrate reservoir hosts. The moderate to severe disease caused by E. chaffeensis in humans, first identified in 1986 and reported for more than 1,000 patients through 2000 ...
Paddock, Christopher D, Childs, James E.
openaire   +5 more sources

Surface-Exposed Proteins ofEhrlichia chaffeensis [PDF]

Infection and Immunity, 2007
ABSTRACTThe surface proteins ofEhrlichia chaffeensisprovide an important interface for pathogen-host interactions. To investigate the surface proteins ofE. chaffeensis, membrane-impermeable, cleavable Sulfo-NHS-SS-Biotin was used to label intact bacteria.
Yasuko Rikihisa, Yan Ge
openaire   +3 more sources

DETECTION OF ANTIBODIES REACTIVE WITH EHRLICHIA CHAFFEENSIS IN THE RACCOON [PDF]

Journal of Wildlife Diseases, 2000
Antibodies reactive with Ehrlichia chaffeensis were detected in raccoon (Procyon lotor) serum samples by using an indirect immunofluorescence assay. Samples from 411 raccoons trapped in the southeastern United States from 1977 to 1999 were tested. Serologically reactive samples with reciprocal titers of > or =16 were detected from 83 raccoons (20 ...
John W. Sumner, James E. Childs, James A. Comer, Christopher D. Paddock, William L. Nicholson   +4 more
openaire   +3 more sources

The developmental cycle of Ehrlichia chaffeensis in vertebrate cells [PDF]

Cellular Microbiology, 2007
Ehrlichia chaffeensis, an obligatory intracellular bacterium, has two forms in mammalian cells: small dense-cored cells (DC) with dense nucleoid and larger reticulate cells (RC) with uniformly dispersed nucleoid. We have determined by electron microscopy that DC but not RC attaches to and enters into the host cells and RC but not DC multiples inside ...
David H. Walker, Si Gao, Jianzhi Zhang, Vsevolod L. Popov, Xue Jie Yu   +4 more
openaire   +3 more sources

Ehrlichia chaffeensis Infections in Drosophila melanogaster [PDF]

Infection and Immunity, 2009
ABSTRACT Ehrlichia chaffeensis is an obligate, intracellular bacterium, transmitted by the tick Amblyomma americanum , and is the causative agent of human monocytic ehrlichiosis infections. We previously demonstrated that E. chaffeensis is capable of growing in
Alison Luce-Fedrow, Tonia Von Ohlen, Stephen K. Chapes   +2 more
openalex   +4 more sources

Experimental infection of dairy calves with Ehrlichia chaffeensis [PDF]

Journal of Medical Microbiology, 2007
Human monocytic ehrlichiosis (HME) is a zoonotic emerging tick-borne disease with clinical signs that range from mild symptoms to multiple organ failure and death.Ehrlichia chaffeensis, the aetiologic agent of HME, is reported to infect a divergent range of mammals.
Kirsten Boughan, David E. Anderson, William G. Bremer, Michael Oglesbee, Brian Rizzo, Jose R. C. delos Santos, L. A. Capitini, Yasuko Rikihisa, Glen R. Needham, Sidney A. Ewing, John J. Schaefer, Roger W. Stich   +11 more
openaire   +3 more sources

Ehrlichia chaffeensis infection in the reservoir host (white-tailed deer) and in an incidental host (dog) is impacted by its prior growth in macrophage and tick cell environments. [PDF]

PLoS ONE, 2014
Ehrlichia chaffeensis, transmitted from Amblyomma americanum ticks, causes human monocytic ehrlichiosis. It also infects white-tailed deer, dogs and several other vertebrates. Deer are its reservoir hosts, while humans and dogs are incidental hosts.
Arathy D S Nair, Chuanmin Cheng, Deborah C Jaworski, Lloyd H Willard, Michael W Sanderson, Roman R Ganta   +5 more
doaj   +1 more source

Experimental infection of Rhipicephalus sanguineus with Ehrlichia chaffeensis [PDF]

Veterinary Microbiology, 2014
Ehrlichia chaffeensis, the etiologic agent of human monocytic ehrlichiosis, is a tick-borne rickettsial pathogen that is infective to a wide range of mammals, including dogs and people. Amblyomma americanum, the lone star tick, is considered the primary vector of E.
Ryan T. Stoffel, Jennifer C. McClure, Marion M. Butcher, Gayle C. Johnson, Will Roland, Chuanmin Cheng, Kamesh R. Sirigireddy, Roman Ganta, Kirstin Boughan, S.A. Ewing, Roger W. Stich   +10 more
openaire   +3 more sources

Comparative Analysis of Wolbachia Genomes Reveals Streamlining and Divergence of Minimalist Two-Component Systems [PDF]

, 2015
Two-component regulatory systems are commonly used by bacteria to coordinate intracellular responses with environmental cues. These systems are composed of functional protein pairs consisting of a sensor histidine kinase and cognate response regulator ...
Christensen, Steen, Serbus, Laura Renee
core   +1 more source

Economic game theory to model the attenuation of virulence of an obligate intracellular bacterium [PDF]

, 2016
Diseases induced by obligate intracellular pathogens have a large burden on global human and animal health. Understanding the factors involved in the virulence and fitness of these pathogens contributes to the development of control strategies against ...
Meyer, Damien, Tago Pacheco, Damian
core   +8 more sources