Results 61 to 70 of about 2,007 (161)

Characterization of an equine macrophage cell line: Application to studies of EIAV infection [PDF]

Veterinary Microbiology, 2009
EIAV is a monocyte/macrophage tropic virus. To date, even though EIAV has been under investigation for numerous years, very few details have been elucidated about EIAV/macrophage interactions. This is largely due to the absence of an equine macrophage cell line that would support viral replication. Herein we describe the spontaneous immortalization and
Isabel, Fidalgo-Carvalho, Jodi K, Craigo, Shannon, Barnes, Carolina, Costa-Ramos, Ronald C, Montelaro   +4 more
openaire   +2 more sources

Real‐Time Reverse Transcription Multienzyme Isothermal Rapid Amplification for Rapid Detection of African Horse Sickness Virus

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
African horse sickness (AHS) is an acute infectious disease of equids caused by the AHS virus (AHSV), which can cause up to 90% mortality in naive horses. Reliable and rapid diagnosis is crucial for the surveillance and control of AHSV. As one of the AHSV detection methods recommended by World Organization for Animal Health (WOAH), the RT‐qPCR assay ...
Chaohua Huang, Jianchang Wang, Zhouxi Ruan, Jiang Wu, Yanxing Lin, Chenfu Cao, Junxing Yang, Qiaoyu Weng, Ye Jin, Peng Chen, Qunyi Hua, Zongfu Wu   +11 more
wiley   +1 more source

Detection of equine infectious anemia viral genome in equids serum samples in Canada

The Microbe
Serum is a suboptimal matrix for detecting Equine Infectious Anemia virus (EIAV) compared to whole blood (WB), which contains mononuclear cells where the virus primarily resides.
Sarah-Jo Paquette, Tara Furukawa-Stoffer, Carolyn James, Nariman Shahhosseini   +3 more
doaj   +1 more source

Dynamical analysis of EIAV infection with cytotoxic T-lymphocyte immune response delay

Results in Applied Mathematics, 2019
This paper deals with a mathematical model for Equine Infectious Anemia Virus (EIAV) infection with Cytotoxic T-lymphocyte (CTL) response delay proposed.
S. Geethamalini, S. Balamuralitharan
doaj   +1 more source

Protective efficacy of centralized and polyvalent envelope immunogens in an attenuated equine lentivirus vaccine. [PDF]

PLoS Pathogens, 2015
Lentiviral Envelope (Env) antigenic variation and related immune evasion present major hurdles to effective vaccine development. Centralized Env immunogens that minimize the genetic distance between vaccine proteins and circulating viral isolates are an ...
Jodi K Craigo, Corin Ezzelarab, Sheila J Cook, Chong Liu, David Horohov, Charles J Issel, Ronald C Montelaro   +6 more
doaj   +1 more source

Serological Examinations of Significant Viral Infections in Domestic Donkeys at the Special Nature Reserve “Zasavica”, Serbia

Animals, 2023
The paper presents the findings of specific antibodies in the blood sera of donkeys against the following viruses: equine infectious anemia virus (EIAV), African horse sickness virus (AHSV), equine herpesvirus type 1 (EHV-1), equine influenza virus ...
Sava Lazić, Sara Savić, Tamaš Petrović, Gospava Lazić, Marina Žekić, Darko Drobnjak, Diana Lupulović   +6 more
doaj   +1 more source

Equine Infectious Anaemia: The Active Surveillance of an Entire Equid Population Reduces the Occurrence of the Infection

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Equine infectious anaemia (EIA) is a life‐long viral infection affecting equids, transmitted mechanically by biting flies and iatrogenic means. Despite its global distribution, active surveillance is limited, with passive clinical surveillance or control of specific equine sectors prevailing. In Italy, a national surveillance plan in horse, donkey, and
Andrea Carvelli, Roberto Nardini, Azzurra Carnio, Ida Ricci, Francesca Rosone, Marcello Sala, Sara Simeoni, Daniela Maccarone, Maria Teresa Scicluna, Serafeim C. Chaintoutis   +9 more
wiley   +1 more source

Broader HIV-1 neutralizing antibody responses induced by envelope glycoprotein mutants based on the EIAV attenuated vaccine

Retrovirology, 2010
Background In order to induce a potent and cross-reactive neutralizing antibody (nAb), an effective envelope immunogen is crucial for many viral vaccines, including the vaccine for the human immunodeficiency virus (HIV).
Liu Lianxing, Wan Yanmin, Wu Lan, Sun Jianping, Li Huiguang, Li Haishan, Ma Liying, Shao Yiming   +7 more
doaj   +1 more source

Role of Angiogenesis and Its Biomarkers in Development of Targeted Tumor Therapies

Stem Cells International, Volume 2024, Issue 1, 2024.
Angiogenesis plays a significant role in the human body, from wound healing to tumor progression. “Angiogenic switch” indicates a time‐restricted event where the imbalance between pro‐ and antiangiogenic factors results in the transition from prevascular hyperplasia to outgrowing vascularized tumor, which eventually leads to the malignant cancer ...
Anchal Pathak, Ajay Kumar Pal, Subhadeep Roy, Mukesh Nandave, Keerti Jain, Shuiqiao Yuan   +5 more
wiley   +1 more source

Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity. [PDF]

PLoS Pathogens, 2013
Lentiviruses can infect non-dividing cells, and various cellular transport proteins provide crucial functions for lentiviral nuclear entry and integration.
Kenneth A Matreyek, Sara S Yücel, Xiang Li, Alan Engelman   +3 more
doaj   +1 more source