Results 71 to 80 of about 2,007 (161)
Inhibition of lentivirus replication by aqueous extracts of
Background Various members of the mint family have been used historically in Chinese and Native American medicine. Many of these same family members, including Prunella vulgaris, have been reported to have anti-viral activities.
Hauck Cathy +7 more
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Equine infectious anemia virus (EIAV) is a member of the Lentivirus genus in the Retroviridae family that exhibits a genomic structure similar to that of HIV-1.
Xue-Feng Wang +8 more
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Structural model of the Rev regulatory protein from equine infectious anemia virus. [PDF]
Rev is an essential regulatory protein in the equine infectious anemia virus (EIAV) and other lentiviruses, including HIV-1. It binds incompletely spliced viral mRNAs and shuttles them from the nucleus to the cytoplasm, a critical prerequisite for the ...
Yungok Ihm +7 more
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Semianalytical solutions by homotopy analysis method for EIAV infection with stability analysis
Equine Infectious Anemia Virus (EIAV) is a bovine lentivirus group that creates equine infectious anemia in horses around the globe. In this paper, we propose a basic nonlinear differential equation for EIAV infection.
S. Geethamalini, S. Balamuralitharan
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The ability to predict the conditions under which antibodies protect against viral infection would transform our approach to vaccine development. A more complete understanding is needed of antibody protection against lentivirus infection, as well as the ...
Elissa J. Schwartz, Robert J. Smith?
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168. EIAV-Based Vectors for the Treatment of Haemophilia A
Effective gene therapy for haemophilia necessitates a vector system that is not subject to a pre-existing immune response, has adequate coding capacity, can transduce non-dividing cells at a relevant site and gives long-term expression. Lentiviral-based vector systems are currently the only integrating vector systems that fulfil these criteria for the ...
openaire +1 more source
Incorporation of Uracil into Viral DNA Correlates with Reduced Replication of EIAV in Macrophages
The retrovirus equine infectious anemia virus (EIAV) encodes a dUTPase situated between reverse transcriptase and integrase. We have described the inability of EIAV with a 270-bp dUTPase deletion, delta DU EIAV, to replicate to wild-type (WT) levels in equine macrophages (D. S. Threadgill, W. K. Steagall, M. T. Flaherty, F. J. Fuller, S. T. Perry, K. E.
Steagall, Wendy K. +4 more
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Apparent elimination of EIAV ancestral species in a long-term inapparent carrier
Equine infectious anemia virus (EIAV) envelope variation produces newly dominant quasispecies with each sequential disease cycle; new populations arise, and previous plasma quasispecies, including the original inoculum, become undetectable. The question remains whether these ancestral variants exist in tissue reservoirs or if the immune system ...
Craigo, Jodi K. +5 more
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From February to December 2021, 960 serum samples from different climate regions in two Mexican states were analyzed for antibodies against EIAV using competitive enzyme-linked immunosorbent assay (cELISA) and agar gel immunodiffusion (AGID) tests.
A. Villa-Mancera +7 more
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Crystallization of EIAV p26 [PDF]
Z. Jin +4 more
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