Results 151 to 160 of about 53,789 (311)
Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve +5 more
wiley +1 more source
Effects of Jack Bean urease on Insect Blood [PDF]
Research Distinction in BiologyJackbean (Canavalia ensiformis) ureases are entomotoxic to hemipteran insects, an effect partially due to the release of internal peptides by insect's cathepsin- like digestive enzymes.
Dyer, Samantha
core
Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri +4 more
wiley +1 more source
Coupling of COX-1 to mPGES1 for prostaglandin E2 biosynthesis in the murine mammary gland
The mammary gland, like most tissues, produces measurable amounts of prostaglandin E2 (PGE2), a metabolite of arachidonic acid produced by sequential actions of two cyclooxygenases (COX-1 and COX-2) and three terminal PGE synthases: microsomal ...
Subhashini Chandrasekharan +5 more
doaj +1 more source
Impact of
Suzanne M. Pilkington +4 more
openalex +1 more source
The discovery of the cannabinoid receptors CB1 and CB2 in 19881,2 and 1990,(3) respectively, and of the endogenous cannabinoid ligands (endocannabinoids) arachidonoylethanolamide (AEA) and 2-arachidonoylglycerol (2-AG) in 1992(4) and 1995,(5 ...
C. Rouzer, L. Marnett
semanticscholar +1 more source
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim +12 more
wiley +1 more source
Leukotrienes (LTs) play major roles in lung immune responses, and LTD4 is the most potent agonist for cysteinyl LT1, leading to bronchoconstriction and tissue remodeling. Here, we studied LT crosstalk between myeloid cells and pulmonary epithelial cells.
Ana Lukic +6 more
doaj +1 more source
The Broad Biological Significance of Eicosanoids in Invertebrates [PDF]
David Stanley, Yonggyun Kim
openalex
This graphical abstract represents the main results of the study. It highlights the plant species under investigation: Lantana camara L. ABSTRACT Inflammation is a complex process associated with various chronic diseases. Lantana camara L., widely used in traditional medicine, exhibits diverse bioactivities, though its effects on lipid metabolism ...
Ari S. de O. Lemos +8 more
wiley +1 more source

