Results 161 to 170 of about 53,789 (311)

Nanomolar EP4 Receptor Potency and Expression of Eicosanoid- Related Enzymes in Normal Appearing Colonic Mucosa From Patients with Colorectal Neoplasia [PDF]

open access: green, 2021
Ulrike Ries Feddersen   +5 more
openalex   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza   +7 more
wiley   +1 more source

Onion (Allium cepa L.) Organosulfur Compounds: From Traditional Use to Modern Pharmacological Insights

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
This review systematically examines the chemical diversity, extraction methods, and pharmacological activities of organosulfur compounds (OSCs) in onions. Key mechanisms include lipid metabolism regulation, anti‐bacterial and anti‐tumor effects, hypoglycemic activity, and anti‐asthmatic potential.
Yuanyuan Tang, De Lv, Yijing Tao
wiley   +1 more source

Nbeal2 Inactivation Triggers Abl1 Stabilisation and Dysregulated Subcellular Localisation of the Multi‐Drug‐Resistant Protein MDR1 (ABCB1) in Mast Cells

open access: yesImmunology, Volume 177, Issue 2, Page 355-369, February 2026.
(A) Proposed model for Abl1 degradation via Nbeal2. Nbeal2 interacts with Abl1 with its WDR domain. This results in proteasomal degradation by a yet unidentified ubiquitin ligase. Therefore, Nbeal2 inactivation stabilises Abl1, which supports mast cell (MC) degeneration. (B) In wt MCs, the Abl1 protein level is controlled by Nbeal2. Furthermore, Nbeal2
Raphaela Marquardt   +10 more
wiley   +1 more source

Inhibition of COX‐2‐mediated eicosanoid production plays a major role in the anti‐inflammatory effects of the endocannabinoid Ndocosahexaenoylethanolamine (DHEA) in macrophages [PDF]

open access: bronze, 2014
Jocelijn Meijerink   +7 more
openalex   +1 more source

Comprehensive Evaluation of Body Lotion in Alleviating Xerosis: A Multi‐Omics Approach to Lipid Metabolism and Microbial Community Modulation

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Xerosis, marked by a compromised skin barrier and disrupted lipid metabolism, leads to dryness, scaling, and itching. Ceramide and natural oil‐based moisturizers can improve skin hydration and barrier repair, but their effects on lipid networks and microbiome interactions have not been well understood.
Jun Wang   +9 more
wiley   +1 more source

Effect of synthetic and bovine milk conjugated linoleic acid (CLA) on immune function : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition Science at Massey University [PDF]

open access: yes, 1999
CLA is a collective name for a mixture of positional and geometrical isomers of linoleic acid (c-9, c-12-octadecadioenic acid) which possess conjugated double bonds.
Zhao, Hui
core  

Incidence Rate of Otitis Externa Episodes in Atopic Dogs Is Reduced by a Therapeutic Diet in a 6‐Month Randomised, Blinded, Controlled, Clinical Trial

open access: yesVeterinary Dermatology, Volume 37, Issue 1, Page 89-102, February 2026.
ABSTRACT Background Recurrent otitis externa (OE) episodes commonly affect dogs with canine atopic dermatitis (cAD) despite ongoing cAD treatment. Objective To determine if a therapeutic diet with active ingredients targeting the skin barrier and allergy pathways reduces the incidence rate of OE.
Adrian Watson   +5 more
wiley   +1 more source

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