Results 241 to 250 of about 33,480 (278)
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Clinics in Chest Medicine, 1989
Eicosanoids are metabolites of the essential fatty acid, arachidonic acid, which is an integral part of all cell membranes. Membrane damage (as in lung injury) and stretching of tissues are recognized stimuli for lung prostaglandin release, indicating a spectrum of possible roles of eicosanoids in the function of the normal and diseased lung.
Kurt R. Stenmark +3 more
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Eicosanoids are metabolites of the essential fatty acid, arachidonic acid, which is an integral part of all cell membranes. Membrane damage (as in lung injury) and stretching of tissues are recognized stimuli for lung prostaglandin release, indicating a spectrum of possible roles of eicosanoids in the function of the normal and diseased lung.
Kurt R. Stenmark +3 more
openaire +3 more sources
New England Journal of Medicine, 1983
Nowadays, bronchial asthma is generally regarded as a disease of allergy. Its expression can be attributed to a constitutional predisposition which not only manifests itself as a hypersensitivity to various allergens, but also as an altered resistance of the airways.1 Fifty years after this formulation of asthma emerged from the school of Clemens von ...
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Nowadays, bronchial asthma is generally regarded as a disease of allergy. Its expression can be attributed to a constitutional predisposition which not only manifests itself as a hypersensitivity to various allergens, but also as an altered resistance of the airways.1 Fifty years after this formulation of asthma emerged from the school of Clemens von ...
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Planta Medica, 1995
Samples of the expressed fixed oil from different sources of Nigella sativa seeds were examined by thin-layer and gas chromatography for content of fixed oils and thymoquinone, and these substances were tested as possible inhibitors of eicosanoid ...
P. Houghton +3 more
semanticscholar +1 more source
Samples of the expressed fixed oil from different sources of Nigella sativa seeds were examined by thin-layer and gas chromatography for content of fixed oils and thymoquinone, and these substances were tested as possible inhibitors of eicosanoid ...
P. Houghton +3 more
semanticscholar +1 more source
Biochemical Society Transactions, 1988
A better understanding of the physiological and pathological roles of lipoxygenase metabolites on skin will be obtained with the development of safe and specific 5- and 12-lipoxygenase inhibitors. Lipocortins have been cloned and the results of clinical trials with them should provide further insight into the mechanism(s) of action of steroids on skin ...
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A better understanding of the physiological and pathological roles of lipoxygenase metabolites on skin will be obtained with the development of safe and specific 5- and 12-lipoxygenase inhibitors. Lipocortins have been cloned and the results of clinical trials with them should provide further insight into the mechanism(s) of action of steroids on skin ...
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The FASEB Journal, 2014
In humans, LL‐37 and eicosanoids are important mediators of inflammation and immune responses. Here we report that LL‐37 promotes leukotriene B4 (LTB4) and thromboxane A2 (TXA2) generation by human monocyte‐derived macrophages (HMDMs).
M. Wan +8 more
semanticscholar +1 more source
In humans, LL‐37 and eicosanoids are important mediators of inflammation and immune responses. Here we report that LL‐37 promotes leukotriene B4 (LTB4) and thromboxane A2 (TXA2) generation by human monocyte‐derived macrophages (HMDMs).
M. Wan +8 more
semanticscholar +1 more source
Eicosanoid Signaling in Insects: from Discovery to Plant Protection
, 2014Prostaglandins (PGs) and related eicosanoids are signal moieties derived from arachidonic acid and two other C20 polyunsaturated fatty acids. They were discovered in the 1930s in the context of mammalian reproductive physiology; PGs were associated with ...
D. Stanley, Yonggyun Kim
semanticscholar +1 more source
The enzymology of human eicosanoid pathways: the lipoxygenase branches
Molecular Biology Reports, 2020R. Biringer
semanticscholar +1 more source
Eicosanoids as modulators of macrophage eicosanoid release
Agents and Actions, 1989A. P. M. Lauwen +3 more
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1988
Psoriasis is prototypic of several inflammatory proliferative skin diseases. Increased proliferation, decreased differentiation and the presence of inflammation are lesional characteristics. We and others have demonstrated that cyclic nucleotides are important regulators of epidermal physiology.
John J. Voorhees +14 more
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Psoriasis is prototypic of several inflammatory proliferative skin diseases. Increased proliferation, decreased differentiation and the presence of inflammation are lesional characteristics. We and others have demonstrated that cyclic nucleotides are important regulators of epidermal physiology.
John J. Voorhees +14 more
openaire +2 more sources