Results 51 to 60 of about 68,592 (324)
Journal of Lipid Research, 2018 Extracellular vesicles (EVs), such as exosomes and microvesicles, are small membrane-bound vesicles released by cells under various conditions. In a multitude of physiological and pathological conditions, EVs contribute to intercellular communication by ...
Eric Boilard
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Molecules, 2020 Nonalcoholic fatty liver disease (NAFLD) is becoming a major public health problem worldwide. The study aimed to evaluate the concentration of eicosanoids in serum and liver tissue during steatosis progression and to assess whether eicosanoid change ...
Dominika Maciejewska +7 more
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Eicosanoids: physiology update and orthodontic implications
Australasian Orthodontic Journal, 1991 The eicosanoids are members of a group of substances comprising prostaglandins and Ieukotrienes which are released by a host of mechanical, thermal, bacterial and other insults and contribute importantly to the signs and genesis of inflammation (Brain ...
Collett Anthony R., Stewart Alastair G.
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Journal of Lipid Research, 2015 Cytochrome P450 (CYP)-dependent eicosanoids comprise epoxy- and hydroxy-metabolites of long-chain PUFAs (LC-PUFAs). In mammals, CYP eicosanoids contribute to the regulation of cardiovascular and renal function. Caenorhabditis elegans produces a large set
Yiwen Zhou +4 more
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Expression of mRNA for phospholipase A(2), cyclooxygenases, and lipoxygenases in cultured human umbilical vascular endothelial and smooth muscle cells and in biopsies from umbilical arteries and veins [PDF]
, 1998 Arachidonic acid (AA) is released by phospholipase A(2) (PLA(2)) and then converted into vasoactive and inflammatory eicosanoids by cyclooxygenases (COX) and lipoxygenases (LOX).
Carlsson, Maria +5 more
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Advanced Materials, EarlyView.The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim +12 more
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Activation and Regulation of Cellular Eicosanoid Biosynthesis
The Scientific World Journal, 2007 There is a growing appreciation for the wide variety of physiological responses that are regulated by lipid messengers. One particular group of lipid messengers, the eicosanoids, plays a central role in regulating immune and inflammatory responses in a ...
Thomas G. Brock, Marc Peters-Golden
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The Role of Eicosanoids in Alzheimer’s Disease
International Journal of Environmental Research and Public Health, 2019 Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders known. Estimates from the Alzheimer’s Association suggest that there are currently 5.8 million Americans living with the disease and that this will rise to 14 million by 2050.
R. Biringer
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Advanced Science, EarlyView.The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher +15 more
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Cancer Medicine, 2022 Background Numerous studies have investigated the possible involvement of eicosanoids, lysophospholipids, and sphingolipids in cancer. We considered that comprehensive measurement of these lipid mediators might provide a better understanding of their ...
Makoto Kurano, Eri Sakai, Yutaka Yatomi
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