Results 51 to 60 of about 5,706 (150)

Eicosanoid Isolation from Mouse Intestinal Tissue for ELISA

Bio-Protocol, 2018
Activation of inflammasomes in peritoneal macrophages and intestinal epithelial cells (IEC) leads to the release of eicosanoids. To assess the amount of eicosanoids released by IEC, lipids need to be isolated from whole tissue previous to analysis by ...
Isabella Rauch
doaj   +1 more source

Cannabinoids and the Endocannabinoid System in the Treatment of Chronic Rhinosinusitis

The Laryngoscope, EarlyView.
The objective of this scoping review is to explore the role of the ECS in the pathophysiology of CRS. We identified five studies, all supporting a common conclusion that the ECS is implicated in regulating cellular inflammatory pathways potentially involved in sinonasal disease.
John J. W. Lee, Amr F. Hamour, Jacob G. J. Wihlidal, John M. Lee, Eric Monteiro, Ewa Poduch, Lakshmi Kotra, Allan D. Vescan   +7 more
wiley   +1 more source

Associations of phthalates, phthalate replacements, and their mixtures with eicosanoid biomarkers during pregnancy

Environment International, 2023
Humans are exposed to complex mixtures of phthalates. Gestational exposure to phthalates has been linked to preeclampsia and preterm birth through potential pathways such as endocrine disruption, oxidative stress, and inflammation.
Seonyoung Park, Amber L. Cathey, Wei Hao, Lixia Zeng, Subramaniam Pennathur, Max T. Aung, Zaira Rosario-Pabón, Carmen M. Vélez-Vega, José F. Cordero, Akram Alshawabkeh, Deborah J. Watkins, John D. Meeker   +11 more
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Eicosanoid Inflammatory Mediators Are Robustly Associated With Blood Pressure in the General Population

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Epidemiological and animal studies have associated systemic inflammation with blood pressure (BP). However, the mechanistic factors linking inflammation and BP remain unknown.
Joonatan Palmu, Jeramie D. Watrous, Kysha Mercader, Aki S. Havulinna, Kim A. Lagerborg, Aaro Salosensaari, Mike Inouye, Martin G. Larson, Jian Rong, Ramachandran S. Vasan, Leo Lahti, Allen Andres, Susan Cheng, Pekka Jousilahti, Veikko Salomaa, Mohit Jain, Teemu J. Niiranen   +16 more
doaj   +1 more source

Exogenous oxidized phytosterol may modulate linoleic acid metabolism through upregulation of fatty acid desaturase in rats

Lipids, EarlyView.
Abstract Previous in vitro studies have indicated that oxidized phytosterol (OPS) exhibits some toxicity; however, the harmful effects of OPS on fatty acid metabolism are not completely understood yet. Therefore, this study examined the effects of exogenous phytosterol (PS) and OPS on growth parameters and lipid metabolism in rats.
Tomonari Koyama, Kyoichi Osada
wiley   +1 more source

Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications

Molecular Nutrition &Food Research, EarlyView.
Omega‐3 fatty acids, derived from dietary sources and supplements, serve as bioactive precursors (ALA, EPA, DHA) that integrate into immune cell membranes. These fatty acids enhance cell membrane fluidity, improve immune cell communication, and modulate key transcription factors like NF‐κB.
Mahmut Bodur, Birsen Yilmaz, Duygu Agagunduz, Yeşim Ozogul   +3 more
wiley   +1 more source

Lung eicosanoids in perinatal rats with congenital diaphragmatic hernia

Mediators of Inflammation, 1997
Abnormal levels of pulmonary eicosanoids have been reported in infants with persistent pulmonary hypertension (PPH) and congenital diaphragmatic hernia (CDH).
H. Ijsselstijn, F. J. Zijlstra, J. P. M. Van Dijk, J. C. De Jongste, D. Tibboel   +4 more
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Inhibitors of Eicosanoid Biosynthesis Reveal that Multiple Lipid Signaling Pathways Influence Malaria Parasite Survival in Anopheles gambiae

Insects, 2019
Eicosanoids are bioactive signaling lipids derived from the oxidation of fatty acids that act as important regulators of immune homeostasis and inflammation.
Hyeogsun Kwon, Ryan C. Smith
doaj   +1 more source

Weakened Airway Epithelial Junctions and Enhanced Neutrophil Elastase Release Contribute to Age‐Dependent Bacteremia Risk Following Pneumococcal Pneumonia

Aging Cell, EarlyView.
During spread of Streptococcus pneumoniae from the lung to the bloodstream, the pneumococcal pore‐forming toxin pneumolysin (PLY) disrupts apical junction complexes (AJCs) and triggers the transmigration of polymorphonuclear leukocytes (PMNs), which secrete tissue‐destructive neutrophil elastase.
Shuying Xu, Tianmou Zhu, Hongmei Mou, Shumin Tan, John M. Leong   +4 more
wiley   +1 more source

Eicosanoids and Eosinophilic Inflammation of Airways in Stable COPD

International Journal of COPD, 2021
Natalia Celejewska-Wójcik,1 Aleksander Kania,1 Karolina Górka,1 Paweł Nastałek,1 Krzysztof Wójcik,2 Anna Gielicz,3 Lucyna Mastalerz,1 Marek Sanak,3 Krzysztof Sładek1 1Department of Pulmonology, 2nd Department of Internal Medicine ...
Celejewska-Wójcik N, Kania A, Górka K, Nastałek P, Wójcik K, Gielicz A, Mastalerz L, Sanak M, Sładek K   +8 more
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