Results 31 to 40 of about 24,894 (189)
Therapeutic Advances in Gastroenterology, 2020 Background: Eicosanoid and related docosanoid polyunsaturated fatty acids (PUFAs) and their oxygenated derivatives have been proposed as noninvasive lipidomic biomarkers of nonalcoholic steatohepatitis (NASH).
Cyrielle Caussy +9 more
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Leukotriene B4 limits the effectiveness of fish oil in an animal model of asthma
Heliyon, 2021 This study aimed to evaluate the levels of eicosanoids derived from arachidonic acid (ARA) in the lungs of asthmatic rats supplemented with fish oil. The present data gives insight into the action of fish oil in asthma, related to its inability to modify
D.T.S.Z. Miranda +4 more
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Современная ревматология, 2016 Inflammation is the most important element in the pathogenesis of major human diseases. It determines the fundamental value of anti-inflammatory therapy in the modern concept of targeted pathogenetic treatment.
A. E. Karateev, T. L. Aleinikova
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Pleiotropic Functions of Cytochrome P450 Monooxygenase-Derived Eicosanoids in Cancer
Frontiers in Pharmacology, 2020 Eicosanoids are a class of functionally bioactive lipid mediators derived from the metabolism of long-chain polyunsaturated fatty acids (PUFAs) mediated by multiple enzymes of three main branches, including cyclooxygenases (COXs), lipoxygenases (LOXs ...
Ying Luo, Jun-Yan Liu
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4 open, 2019 Inflammation is the body's reaction to pathogenic (biological or chemical) stimuli and covers a burgeoning list of compounds and pathways that act in concert to maintain the health of the organism.
Brücher Björn L.D.M., Jamall Ijaz S.
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Journal of Lipid Research, 2018 Extracellular vesicles (EVs), such as exosomes and microvesicles, are small membrane-bound vesicles released by cells under various conditions. In a multitude of physiological and pathological conditions, EVs contribute to intercellular communication by ...
Eric Boilard
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浙江大学学报. 农业与生命科学版, 2016 Eicosanoids, which mediate various physiological and pathophysiological processes, are mainly formed from C20 polyunsaturated fatty acids (PUFAs) such as arachidonic acid (AA,20:4n-6) and eicosapentaenoic acid (EPA,20:5n - 3) through cyclooxygenases (COX)
TAN Liangliang, SHEN Lirong
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Cancer Medicine, 2022 Background Numerous studies have investigated the possible involvement of eicosanoids, lysophospholipids, and sphingolipids in cancer. We considered that comprehensive measurement of these lipid mediators might provide a better understanding of their ...
Makoto Kurano, Eri Sakai, Yutaka Yatomi
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Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Advanced Science, EarlyView.Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
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Eicosanoids: physiology update and orthodontic implications
Australasian Orthodontic Journal, 1991 The eicosanoids are members of a group of substances comprising prostaglandins and Ieukotrienes which are released by a host of mechanical, thermal, bacterial and other insults and contribute importantly to the signs and genesis of inflammation (Brain ...
Collett Anthony R., Stewart Alastair G.
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