Results 21 to 30 of about 31,692 (187)
Metabolites, 2022 Eicosanoids are lipid mediators generated from arachidonic acid with pro- and anti-inflammatory properties. Despite these lipid mediators being known for decades, quantitative determination in biological samples is still challenging due to low abundance,
Louis Schmidt +4 more
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Leukotriene B4 limits the effectiveness of fish oil in an animal model of asthma
Heliyon, 2021 This study aimed to evaluate the levels of eicosanoids derived from arachidonic acid (ARA) in the lungs of asthmatic rats supplemented with fish oil. The present data gives insight into the action of fish oil in asthma, related to its inability to modify
D.T.S.Z. Miranda +4 more
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Study of the role of cytosolic phospholipase A2 alpha in eicosanoid generation and thymocyte maturation in the thymus. [PDF]
PLoS ONE, 2015 The thymus is a primary lymphoid organ, home of maturation and selection of thymocytes for generation of functional T-cells. Multiple factors are involved throughout the different stages of the maturation process to tightly regulate T-cell production ...
Matthieu Rousseau +5 more
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Therapeutic Advances in Gastroenterology, 2020 Background: Eicosanoid and related docosanoid polyunsaturated fatty acids (PUFAs) and their oxygenated derivatives have been proposed as noninvasive lipidomic biomarkers of nonalcoholic steatohepatitis (NASH).
Cyrielle Caussy +9 more
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Pleiotropic Functions of Cytochrome P450 Monooxygenase-Derived Eicosanoids in Cancer
Frontiers in Pharmacology, 2020 Eicosanoids are a class of functionally bioactive lipid mediators derived from the metabolism of long-chain polyunsaturated fatty acids (PUFAs) mediated by multiple enzymes of three main branches, including cyclooxygenases (COXs), lipoxygenases (LOXs ...
Ying Luo, Jun-Yan Liu
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The Role(s) of Eicosanoids and Exosomes in Human Parturition
, 2020 The roles that eicosanoids play during pregnancy and parturition are crucial to a successful outcome. A better understanding of the regulation of eicosanoid production and the roles played by the various end products during pregnancy and parturition has ...
Mosaad, E +4 more
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, 2019 Trauma or infection can result in tissue damage, which needs to be repaired in a well-orchestrated manner to restore tissue function and homeostasis. Lipid mediators derived from arachidonic acid (termed eicosanoids) play central and versatile roles in ...
Esser-von Bieren, J.
core +1 more source
Esterified eicosanoids: Generation, characterization and function [PDF]
, 2012 Eicosanoids are oxidation products of C20 polyunsaturated fatty acids (e.g. arachidonic acid) that include prostaglandins, thromboxanes, leukotrienes and hydroperoxy fatty acids. They have important biological roles in vivo, including regulation of renal,
Valerie B. O'Donnell +5 more
core +1 more source
Journal of Lipid Research, 2018 Extracellular vesicles (EVs), such as exosomes and microvesicles, are small membrane-bound vesicles released by cells under various conditions. In a multitude of physiological and pathological conditions, EVs contribute to intercellular communication by ...
Eric Boilard
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Molecules, 2020 Nonalcoholic fatty liver disease (NAFLD) is becoming a major public health problem worldwide. The study aimed to evaluate the concentration of eicosanoids in serum and liver tissue during steatosis progression and to assess whether eicosanoid change ...
Dominika Maciejewska +7 more
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