Results 51 to 60 of about 24,894 (189)

Host/Malassezia Interaction: A Quantitative, Non-Invasive Method Profiling Oxylipin Production Associates Human Skin Eicosanoids with Malassezia

Metabolites, 2021
Malassezia are common components of human skin, and as the dominant human skin eukaryotic microbe, they take part in complex microbe–host interactions. Other phylogenetically related fungi (including within Ustilagomycotina) communicate with their plant ...
Yohannes Abere Ambaw, Martin P. Pagac, Antony S. Irudayaswamy, Manfred Raida, Anne K. Bendt, Federico T. Torta, Markus R. Wenk, Thomas L. Dawson   +7 more
doaj   +1 more source

Systemic Lipid Peroxidation and Colorectal Cancer Risk: A Time‐Varying Relationship

International Journal of Cancer, EarlyView.
Experimental studies in animals suggest that oxidative stress (OxS) declines as cancer progresses. Whether this occurs in humans, however, remains unclear. The authors of the present study addressed this question by analyzing lipid, DNA, and RNA oxidation biomarkers in relation to colorectal cancer (CRC) risk in patients from Shanghai and the United ...
Gong Yang, Ginger L. Milne, Marina S. Nogueira, Yu‐Tang Gao, Qing Lan, Haoyang Yi, Xiao‐Ou Shu, Wei Zheng, Qingxia Chen   +8 more
wiley   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

Expression and Function of Eicosanoid-Producing Cytochrome P450 Enzymes in Solid Tumors

Frontiers in Pharmacology, 2020
Oxylipins derived from the oxidation of polyunsaturated fatty acids (PUFAs) act as important paracrine and autocrine signaling molecules. A subclass of oxylipins, the eicosanoids, have a broad range of physiological outcomes in inflammation, the immune ...
Eric A. Evangelista, Christi W. Cho, Theresa Aliwarga, Rheem A. Totah   +3 more
doaj   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Eicosanoid Isolation from Mouse Intestinal Tissue for ELISA

Bio-Protocol, 2018
Activation of inflammasomes in peritoneal macrophages and intestinal epithelial cells (IEC) leads to the release of eicosanoids. To assess the amount of eicosanoids released by IEC, lipids need to be isolated from whole tissue previous to analysis by ...
Isabella Rauch
doaj   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster

Journal of Lipid Research
: Eicosanoids are a class of molecules derived from C20 polyunsaturated fatty acids (PUFAs) that play a vital role in mammalian and insect biological systems, including development, reproduction, and immunity.
Pakeeza Azizpor, Ogadinma K. Okakpu, Sophia C. Parks, Diego Chavez, Fayez Eyabi, Stephanie Martinez-Beltran, Susan Nguyen, Adler R. Dillman   +7 more
doaj   +1 more source

Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases

Journal of Lipid Research, 2003
Arachidonic acid inhibits adipocyte differentiation of 3T3-L1 cells via a prostaglandin synthesis-dependent pathway. Here we show that this inhibition requires the presence of a cAMP-elevating agent during the first two days of treatment.
Rasmus K. Petersen, Claus J⊘rgensen, Arild C. Rustan, Livar Fr⊘yland, Karin Muller-Decker, Gerhard Furstenberger, Rolf K. Berge, Karsten Kristiansen, Lise Madsen   +8 more
doaj   +1 more source