Results 111 to 120 of about 291,615 (215)

The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans. [PDF]

Front Cell Dev Biol, 2023
Ma Z, Horrocks J, Mir DA, Cox M, Ruzga M, Rollins J, Rogers AN.   +6 more
europepmc   +1 more source

Changes in the phosphorylation of initiation factor eIF‐2α, elongation factor eEF‐2 and p70 S6 kinase after transient focal cerebral ischaemia in mice [PDF]

, 2001
Sonja Althausen, Thorsten Mengesdorf, Günter Mies, László Oláh, Angus C. Nairn, Christopher G. Proud, Wulf Paschen   +6 more
openalex   +1 more source

The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids

Molecular and Cellular Biology, 1995
S. A. Wek, Shuhao Zhu, R. Wek
semanticscholar   +1 more source

Characterization of double-stranded-RNA-activated kinase that phosphorylates α subunit of eukaryotic initiation factor 2 (eIF-2α) in reticulocyte lysates

, 1980
Daniel H. Levin, R Petryshyn, Irving M. London   +2 more
openalex   +1 more source

Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

Molecular and Cellular Biology, 1995
P. Romano, S. R. Green, Glen N. Barber, Michael B. Mathews, A. Hinnebusch   +4 more
semanticscholar   +1 more source

Decreased eukaryotic initiation factors expression upon temozolomide treatment-potential novel implications for eIFs in glioma therapy. [PDF]

J Neurooncol, 2023
Krassnig S, Leber SL, Orthmann A, Golob-Schwarzl N, Huber HJ, Wohlrab C, Skofler C, Pennauer M, Raicht A, Birkl-Toeglhofer AM, Naumann M, Mahdy-Ali K, von Campe G, Leoni M, Alcaniz J, Hoffmann J, Wälchli T, Weis S, Benesch M, Haybaeck J.   +19 more
europepmc   +1 more source

Hsp90 mediates activation of the heme regulated eIF-2 alpha kinase during oxidative stress.

Indian journal of biochemistry & biophysics, 2010
The heme-regulated inhibitor (HRI), a member of the eIF-2 alpha kinase family is crucial for regulating protein synthesis during stress. In addition to heme, stress proteins Hsp90 and Hsp70 are known to regulate HRI. The present study aims to determine the physical association of these Hsps in the regulation of HRI activation during oxidative stress ...
A P, Kulkarni, S P, Mittal, T P A, Devasagayam, J K, Pal   +3 more
openaire   +1 more source

Binding of the Influenza Virus NS1 Protein to Double-Stranded RNA Inhibits the Activation of the Protein Kinase That Phosphorylates the eIF-2 Translation Initiation Factor

, 1995
Lu Yuan, Marlene Wambach, Michael G. Katze, Robert M. Krug   +3 more
openalex   +1 more source

Rhodosporidium toruloides-a new surrogate model to study rapamycin induced effects on human aging and cancer. [PDF]

Cell Mol Life Sci
Cavelius PM, Haack M, Awad D, Brueck TB, Mehlmer N.   +4 more
europepmc   +1 more source

The ability of dietary essential oils to mitigate nickel-induced growth retardation, immune-antioxidant suppression, and endoplasmic reticulum stress activation in Nile tilapia. [PDF]

Fish Physiol Biochem
Ahmed SAA, El-Rahman GIA, Mohammed HA, Abdo SA, Aly MYM, Ghannam HE, Mahsoub F, Khamis T, Ibrahim RE.   +8 more
europepmc   +1 more source