Results 141 to 150 of about 35,642 (231)

Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake [PDF]

, 2016
Sarah Kobylewski, Kimberly A. Henderson, Kristin Yamada, Curtis D. Eckhert   +3 more
openalex   +1 more source

Supplementary Figure 5 from Adaptive Basal Phosphorylation of eIF2α Is Responsible for Resistance to Cellular Stress–Induced Cell Death in <i>Pten</i>-Null Hepatocytes [PDF]

, 2023
Ni Zeng, Yang Li, Lina He, Xiaoling Xu, Vivian Galicia, Chu‐Xia Deng, Bangyan L. Stiles   +6 more
openalex   +1 more source

Mitochondrial presequences are more than just address labels

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Most mitochondrial proteins are synthesized in the cytosol as precursor proteins with N‐terminal presequences. These presequences serve as targeting signals that facilitate the binding to mitochondrial surface receptors and translocation across the mitochondrial membranes.
Erik Marcel Heller, Svenja Lenhard, Doron Rapaport, Johannes Herrmann   +3 more
wiley   +1 more source

The endoplasmic reticulum in mitochondrial protein targeting: A neuronal perspective on organelle crosstalk

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Neurons depend on tightly regulated spatial proteostasis to maintain function across their extended morphology. The endoplasmic reticulum (ER), traditionally known for its function in protein synthesis, folding, and trafficking, has long been recognized as a central platform for directing proteins to organelles of the secretory and endocytic ...
J. Tabitha Hees, Angelika B. Harbauer
wiley   +1 more source

eIF2α phosphorylation controls thermal nociception

, 2016
Arkady Khoutorsky, Robert E. Sorge, Masha Prager‐Khoutorsky, Sophie Anne Pawlowski, Geraldine Longo, Seyed Mehdi Jafarnejad, Soroush Tahmasebi, Loren J. Martin, Mark H. Pitcher, Christos G. Gkogkas, Reza Sharif‐Naeini, Alfredo Ribeiro‐da‐Silva, Charles W. Bourque, Fernando Cerveró, Jeffrey S. Mogil, Nahum Sonenberg   +15 more
openalex   +2 more sources

Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice [PDF]

, 2017
Allagnat, Allen, Atkins, Auerbuch, Bettigole, Blalock, Calfon, Carrero, Carrero, Carrero, Carrero, Celada, Cho, Cullinan, Cullinan, Czuczman, Dabo, Edelson, Endo, Farrand, Ferlito, Fonseca, Gaillard, Gekara, Glomski, Grabiner, Gusella, Guzmán, Hamon, Han, Harding, Harding, Harding, Hassan, Hetz, Hiramatsu, Inaba, Ingrand, Ishibashi, Jammi, Kozutsumi, Köster, Lam, Li, Martinon, Masuoka, McCaffrey, Merquiol, Nakamura, Novoa, O'Connell, O'Riordan, Okumura, Oyadomari, Pasqual, Pavio, Peña, Portnoy, Sauer, Scheuner, Seimon, Stavru, Stockinger, Stockinger, Tabas, Tardif, Vattem, Walter, Wheeler, Woo, Yamamoto, Zinszner   +71 more
core   +2 more sources

Trends in Dietary Exosome‐Like Nanoparticles: Preparation, Nutritional Functions, Bioactive Delivery Efficacy, Human Health Effects, and Future Product Development

Small Structures, Volume 7, Issue 3, March 2026.
This graphical abstract summarizes the current advances in dietary exosome‐like nanoparticles (ELNs), highlighting their biogenesis pathways (MVB‐dependent, vacuole‐mediated, and EXPO routes), molecular composition (nucleic acids, lipids, proteins, and bioactive compounds), and major preparation strategies including differential ultracentrifugation ...
Nidesha Randeni, Jinhai Luo, Min‐Hsiung Pan, Baojun Xu   +3 more
wiley   +1 more source

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, Volume 59, Issue 3, March 2026.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source

Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2α Phosphorylation in Caenorhabditis elegans [PDF]

, 2017
Warakorn Kulalert, Harini Sadeeshkumar, Ying K. Zhang, Frank C. Schroeder, Dennis H. Kim   +4 more
openalex   +1 more source

Additional file 10: of eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet

, 2017
Woo-Gyun Choi, Jaeseok Han, Ji-Hyeon Kim, Mi-Jeong Kim, Jae-Woo Park, Benbo Song, Hee-Jeong Cha, Hye‐Seon Choi, Hun-Taeg Chung, In-Kyu Lee, Tae‐Sik Park, Maria Hatzoglou, Hueng-Sik Choi, Hyun Yoo, Randal Kaufman, Sung Back   +15 more
openalex   +1 more source