Results 151 to 160 of about 27,813 (194)

The dual role of ATF4 in neurons: from stress adaptation to therapeutic intervention. [PDF]

Front Mol Neurosci
Huang H, Xu Y, Li X, Li C, Peng W.
europepmc   +1 more source

Contactin-2 mitigates heart failure and cardiac remodeling via regulation of NUPR1 and ferroptosis. [PDF]

Biol Direct
Fei YD, Wei ZX, Chen TZ, Zhang LH, Zhang YC, Hou JW, Wang Q, Cai XX, Chen M, Yang YL, Yao PC, Fei ZT, Bai Y, Zhao TT, Yan J, Li W, Yang M, Zhang R, Liu XD, Zhao MZ, Xu XL, Sun J, Wang YP, Li YG.   +23 more
europepmc   +1 more source

Cigarette Smoke Induces Canonical Stress Granule Formation in Human Bronchial Epithelial Cells in Reactive Oxygen Species- and PERK-Dependent Manners. [PDF]

Biomolecules
Bhowmik M, Zheng C, Bekele B, Failler J, Klatt C, Farimani S, Jones B, Tyan CC, Abu-Arish A.   +8 more
europepmc   +1 more source

Immune checkpoint inhibitor-driven smooth muscle cell phenotypic modulation: a potential contributor to atherosclerotic risk associated with these therapies. [PDF]

Front Cardiovasc Med
Chattopadhyay A, Dosunmu AO, Reddy D, Dharma S, Panchal K, Kwartler CS, Milewicz DM.   +6 more
europepmc   +1 more source

Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation. [PDF]

PLoS Pathog
Chen J, Fan J, Qin M, Lin Z, Mu S, Dai L, Qin Z.   +6 more
europepmc   +1 more source

Equine infectious anemia virus blocks interferon responses through Rev-mediated activation of the stress granule-PKR-eIF2α pathway. [PDF]

PLoS Pathog
Ren H, Chen K, Zhou B, Zhang W, Wang XF, Wang X.   +5 more
europepmc   +1 more source

The unfolded protein response and its activation by insulin in muscle are not altered by obesity or type 2 diabetes. [PDF]

Clin Sci (Lond)
Kruse R, Kristensen JM, Vind BF, Juhl S, Stidsen JV, Sabaratnam R, Højlund K.   +6 more
europepmc   +1 more source

Uridine analogs prevent stress granule formation, not by blocking PKR recognition, but by inhibiting the synthesis of T7 RNA polymerase byproducts. [PDF]

RNA
Ihn SJ, Jiang E, Kejiou NS, Wang YE, Farlam-Williams L, Palazzo AF, Lee HO.   +6 more
europepmc   +1 more source

Centrosome linker protein CEP68 modulates cellular stress responses via nuclear condensate formation and HSP27 interaction. [PDF]

iScience
Hung HF, Zhu PP, Blackstone C.
europepmc   +1 more source

Cell-type-specific role of eiF2α pathway human Alzheimer’s disease brains

Protein synthesis is required for the consolidation of short-term memory into long-term memory, and it is regulated by various signaling pathways including the eIF2α pathway. The eIF2α pathway bidirectionally regulates the initiation of protein synthesis
Olotu , Samuel O.A.
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