Results 61 to 70 of about 2,149 (169)
Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar +2 more
wiley +1 more source
Antivenoms, obtained by venom immunization, have narrow species coverage due to low immunogenicity of venom neurotoxins. Here the authors immunize horses with a designed recombinant consensus neurotoxin, and the resulting antisera protect mice from ...
Guillermo de la Rosa +5 more
doaj +1 more source
Coral snake venoms: mode of action and pathophysiology of experimental envenomation
Coral snakes, the New World Elapidae, are included in the genera Micniroides and Micrurus. The genus Mlcrurus comprises nearly all coral snake species and those which are responsible for human snake-bite accidents.
Oswald Vital Brazil
doaj +1 more source
Snakes on Trains: Railways May Sway Goa's King Cobra Distribution
Distribution of King Cobras (Ophiophagus kaalinga) across Goa, India, shows occurrence in climatically suitable forests and, notably, also along low‐suitability railway corridors, suggesting that snakes may be accidentally transported on trains, leading to range expansion.
Dikansh S. Parmar +4 more
wiley +1 more source
Elapid venom toxins: multiple recruitments of ancient scaffolds [PDF]
Nigroxins A and B, two myotoxic phospholipases A2 (PLA2s) from the venom of the American elapid Micrurus nigrocinctus, belong to a new PLA2 subclass. Their primary structures were established and compared with those of PLA2s that have already been studied with respect to myotoxic activity.
Alape Girón, Alberto +7 more
openaire +4 more sources
Snakebite envenomation remains an important public health concern in Namibia, particularly following bites from the zebra spitting cobra (Naja nigricincta nigricincta) and the puff adder (Bitis arietans). However, the clinical presentations and management outcomes of these snakebites remain poorly characterized.
Katrina Ndongi +3 more
wiley +1 more source
Snakebite envenomation requires rapid venom identification for effective treatment, a need unmet by current diagnostics in China. This study aimed to develop a rapid, multiplex immunofluorescence lateral flow assay for the simultaneous detection of four major venomous snakes: Deinagkistrodon acutus, Bungarus multicinctus, Naja atra, and Agkistrodon ...
Linsheng Zeng +13 more
wiley +1 more source
ABSTRACT Quaternary climatic fluctuations had a substantial influence on ecosystems, species distribution, phenology and genetic diversity, driving extinction, adaptation and demographic shifts during glacial periods and postglacial expansions. Integration of genomic data and environmental niche modelling can provide valuable insights on how organisms ...
Marcella Sozzoni +16 more
wiley +1 more source
Many prey species detect chemical cues from predators and modify their behaviours in ways that reduce their risk of predation. Theory predicts that prey should modify their anti-predator responses according to the degree of threat posed by the predator ...
Jonathan K. WEBB, Weiguo DU, David PIKE, Richard SHINE
doaj
Snake envenomation is an important medical problem. One of the hurdles in antivenom development is the in vivo assay of antivenom potency which is expensive, gives variable results and kills many animals.
Kavi Ratanabanangkoon +9 more
doaj +1 more source

