Results 181 to 190 of about 62,911 (266)

Beyond Hemostasis: Platelet Biomarkers and Vascular‐Immune Crosstalk in Dengue

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Several biomarkers are associated with platelet activation during dengue virus (DENV) infection. These include serum markers (AST, ALT, ferritin), platelet surface or secreted molecules (P‐selectin, PF4, RANTES, VEGF‐A, CD40L, TREM‐1, TLT‐1), immune and endothelial markers (TREM‐1, Ang‐1, Ang‐2), and viral components such as DENV EIII.
Amanda Beatriz Adriano da Silva‐Alencar, Amanda de Oliveira Matos, Daniel Francisco de Sousa, Jefferson do Carmo Dietz, Eugenio Damaceno Hottz, Marcelle Figueira Marques da Silva‐Sales, Helioswilton Sales‐Campos   +6 more
wiley   +1 more source

Utility of Fecal Elastase-1 in Estimating Exocrine Pancreatic Function in Cystic Fibrosis: A Scoping Review. [PDF]

Pediatr Pulmonol
Sankararaman S, Hendrix S, Neudecker M, Borowitz D.   +3 more
europepmc   +1 more source

Expanding the Toolbox for Biocatalytic Halogenation by Identification and Characterization of Three Vanadium Chloroperoxidases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Schematic illustration of the workflow from DNA sequence‐based research to expression in shaking flasks and subsequent purification via IMAC. The obtained enzymes broaden the toolbox of enzymes used for halogenation reactions with differing catalytic properties and tolerances to reaction‐related conditions.
Sonja Schönrock, Nils Senge, Dirk Holtmann   +2 more
wiley   +1 more source

Disparities in the diagnosis and management of exocrine pancreatic insufficiency in resectable vs metastatic pancreatic cancer. [PDF]

Oncologist
Ni P, Baglini C, Meurer J, Drapek L, Dhandibhotla S, Liu Y, Bazerbachi F, Weekes C, Ting DT, Kambadakone A, Fernandez-Del Castillo C, Hernandez-Barco YG.   +11 more
europepmc   +1 more source

N‐Amidinyl‐Benzodiazaborines as Novel Boron‐Based Scaffolds: Synthesis and Application in Retromer Stabilization

Advanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
In this work, we successfully synthesized a library of novel N‐amidinyl‐benzodiazaborines, showing how these heteroaryl guanyl hydrazones are able to stabilize the retromer, a protein complex involved in the disposal of misfolded and aggregated proteins, whose malfunction is observed in multiple neurodegenerative diseases.
Alessandro Dimasi, Arianna Montoli, Michele Buonaguro, Leonardo Maiorana, Giovanni Macetti, Eleonora Colombo, Luca Muzio, Greta Donati, Daniele Passarella, Pierfausto Seneci, Valerio Fasano   +10 more
wiley   +1 more source

Effects of quercetin, baicalein, azithromycin, and their combination on biofilm formation, virulence factors and gene expression associated with Pseudomonas aeruginosa quorum sensing. [PDF]

Mol Biol Rep
Parra Rodríguez V, Gómez V, Pabón LC, Hernández-Rodríguez P.   +3 more
europepmc   +1 more source

Pancreas, Muscle, and Subcutaneous Fat Atrophy in Patients Undergoing Radiation for Neuroblastoma

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background/Objectives Radiation therapy (RT) is part of standard‐of‐care therapy in high‐risk neuroblastoma (HR‐NBL) but can significantly affect nearby tissue. The objectives of this study were (1) to characterize changes in pancreas volume after RT and (2) to characterize changes in body composition, including body weight percentile ...
Pradipta Debnath, Marissa Ray, Luke Pater, Alexandra O. Glenn, Stephen Hartman, Elanchezhian Somasundaram, Todd Jenkins, Juan P. Gurria, Katherine Somers, Andrew T. Trout, Meera Kotagal   +10 more
wiley   +1 more source

Dimethyl Sulfoxide Enhances HLA Peptide Identification. [PDF]

Proteomes
Lim Kam Sian TCC, Ding Y, Blundell SA, Schittenhelm RB, Faridi P.   +4 more
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Beyond adrenal fatigue: reframing the adrenal stress index through neutrophil-mediated glucocorticoid resistance. [PDF]

Front Endocrinol (Lausanne)
Cardillo G.
europepmc   +1 more source