Results 201 to 210 of about 115,118 (303)

Psoriasis patients with psoriatic arthritis demonstrate a reduced regulatory capacity for neutrophil elastase. [PDF]

Rheumatology (Oxford)
Macleod T, Dubash SR, Hyde I, Michelena X, Berekmeri A, Helliwell PS, Kingsbury SR, Laws P, Mankia K, Stacey M, Marzo-Ortega H, Wittmann M.   +11 more
europepmc   +1 more source

Bulk density-calibrated fiber networks reveal local weakness as the driver of protease-dependent aortic failure. [PDF]

Int J Eng Sci
Gueldner PH, Agrawal Y, Rajagopal KR, Vorp DA, Maiti S.   +4 more
europepmc   +1 more source

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, Volume 100, Issue 4, Page 824-840, October 2026.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

An endothelium-derived elastase as mediator of shear stress-induced outside-in signaling via integrin alphavbeta3 [PDF]

, 2010
Hennig, Theres
core   +1 more source

SGLT2 Inhibitors Attenuate Neutrophil-Mediated Endothelial Injury in Coronary Artery Disease With Type 2 Diabetes Mellitus Through a GREM1-Associated Smad Signaling Axis. [PDF]

J Cardiovasc Pharmacol
Zheng W, Zhou Y, Ye B, Hu S, Zhang J, Li Z, Chen X, Cao J, Qian J, Ge J.   +9 more
europepmc   +1 more source

Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases

Pharmacological Reviews, 2010
B. Korkmaz, M. Horwitz, D. Jenne, F. Gauthier   +3 more
semanticscholar   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2605-2612, October 2026.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

Comparative Investigation of Red Wine Concentrates as Multifunctional Skin-Protective Agents. [PDF]

Pharmaceutics
Ilić G, Beara I, Milovanović L, Jovanović A, Dekanski D, Pirković A.   +5 more
europepmc   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

Diagnostic Accuracy of Salivary Periodontal Biomarkers Is Reduced in Patients With Crohn's Disease. [PDF]

Clin Exp Dent Res
Toivanen A, Nur, Räisänen I, Gürsoy M, Gürsoy UK, Sorsa T, Rautava J.   +6 more
europepmc   +1 more source